Spring Festival travel rush is about to start in 2024! What is the overall situation? A set of numbers is the first to know

  Spring Festival travel rush is about to kick off in 2024. On January 25th, Railway 12306 began to sell tickets for February 8th (the 29th day of the twelfth lunar month). Passengers who need to book tickets hurry to grab tickets. What is the general situation in Spring Festival travel rush this year? A set of numbers look first!

  7.2 billion

  It is estimated that during the period of Spring Festival travel rush this year, the cross-regional personnel flow will reach 9 billion person-times, nearly twice that of the same period in 2023. According to the forecast, there are about 7.2 billion passenger trips of non-operating minibuses on expressways and ordinary national and provincial trunk lines in Spring Festival travel rush, and the proportion of self-driving trips in the total social travel will exceed 80%.

  18.937 million

  Statistics show that on January 23rd, the national railways sold 18.937 million tickets, a single-day high since Spring Festival travel rush sold tickets, which indicates that the pre-holiday ticket sales peak has arrived.

  61.08 million

  Since the ticket sales in Spring Festival travel rush on January 12th, a total of 190 million train tickets have been sold, including 61.08 million tickets during Spring Festival travel rush, up 159% year-on-year.

Is curcumin, the "new star" of anti-aging, a complete scam?

Original Time School Research Institute Time School is included in the topic # 56 anti-aging substances.

editorial comment/note

Curcumin, which is a’ youth medicine’ and a delicious food, has always had its own place in the anti-aging circle, but it is safe and has no toxic and side effects, but it has not yet been among the top anti-aging products. If you want to listen carefully to the reasons, let’s start with the story of curcumin. ……

Last time, we talked about that a large number of cellular, molecular and clinical studies have proved that curcumin has multiple effects such as anti-inflammatory, anti-oxidation, anti-cancer and anti-microbial (click Review:), but why hasn’t curcumin been licensed and can’t it play a higher role in disease treatment?

Look at people by their character, and look at chemicals by their physical and chemical properties. First of all, we should grasp two characteristics of curcumin: low solubility and unstable chemical properties. Remember these two clues, and the following stories are based on them ~

Low solubility

There is a large hydrophobic region in the molecular structure of curcumin, which determines its basic characteristics of low water solubility. However, there are three hydroxyl groups in its molecular structure, so when the alkalinity is high enough, the charged hydrogen ions will be dissociated, and the curcumin molecule will also be negatively charged, and the water solubility will increase [1]. To put it simply, it is insoluble in water, and the more alkaline it is, the more soluble it is.

instability

Curcumin is a difficult master, and it will change when the environment is a little unsatisfactory. As mentioned above, the greater the alkalinity of the solution, the more curcumin is dissolved, which provides great convenience for the hydrolysis reaction; In addition, curcumin is also easy to occur in the presence of light; What’s more, curcumin may spontaneously oxidize when there is no stimulus! Although so many degradation products have more or less anti-inflammatory and anti-cancer effects, the "periphery" is not as powerful as the "main body" [2].

Then we need to know what curcumin has experienced from eating to discharging, as shown in the following figure [3]:

There are three paths for curcumin to enter digestive tract.

1. In the original form, excreted by feces, jump to the ending 1.

2. After being metabolized by enzymes in digestive tract, it is excreted by feces in the form of metabolites, and jumps to the end 1.

3. Escaped from the clutches of digestive tract enzymes, successfully approached intestinal epithelial cells and entered path B.

There are two ways for curcumin to get close to intestinal epithelial cells.

1. Thrown back to the intestine by the ruthless porters of intestinal epithelial cells, and returned to the path A.

2. Being sent into the blood circulation by the friendly porters of intestinal epithelial cells and entering the path C.

There are two ways for curcumin to reach the liver after it enters the blood circulation.

1. It is metabolized by enzymes in the liver and enters the systemic blood circulation in the form of metabolites, and enters the path D.

2. Escaped from the clutches of liver enzymes, and entered the systemic blood circulation in its original form, and also entered the path D.

After curcumin or its metabolites enter the systemic blood circulation, there are two paths.

1. Enter the kidney with blood, then enter the urine, and pass out of the body with urine, and jump to the end 2.

2. With the distribution of blood to various organs and tissues of the whole body (such as brain, lung, heart, muscle, etc.), it plays an anti-inflammatory, anti-oxidation and anti-cancer role, and jumps to the ending 3.

Obviously, we have high hopes for the ending 3, but how many "difficulties and dangers" does curcumin have to go through to get on this right path? And don’t forget curcumin’s bad temper (low solubility and low stability), so it is even more difficult for it to "survive" success. Therefore, scientists have developed a lot of equipment for curcumin in order to help it succeed.

The role played by these equipments can be summarized as two aspects:

On the one hand, it improves its basic performance (increasing solubility and stability), and on the other hand, it specifically resists "enemy" forces (such as antagonistic cell efflux transporters). The following table is a summary of various methods and principles to improve the absorption and utilization rate of curcumin [3]:

Method type

give an example

principle

Control environmental conditions

Use organic solvents

Increase solubility

Adjust pH

Increase stability

Combined adjuvant

Piperine, catechin, etc.

Inhibition of efflux transporter

Antioxidants such as ascorbic acid and gallic acid.

Increase stability and reduce oxidative degradation.

Packaging technology/carrier technology

Micellar, microemulsion, hydrophobic biopolymer particles, liposomes, etc.

Increase dispersibility in water; Isolate water phase to increase stability; Increase the affinity with tissues and cells

In the research of pushing curcumin into clinical application, the obstacles encountered are not only the above physical and chemical characteristics and biological characteristics of curcumin, but also the research itself:

First of all, curcumin used in various studies is actually different. Most crude extracts made from turmeric and even some refined "curcumin" raw materials contain three main compounds: curcumin, demethoxycurcumin and bis-demethoxycurcumin, and a few secondary metabolites.

The ratio of curcumin compounds in various "curcumin preparations" is different, and the types of curcumin compounds used in experimental research are also different (pure curcumin is often used in in vitro research and more is artificially synthesized, while the mixture of curcumin compounds is often used in in in vivo research and clinical trials), but curcumin is often used as the active ingredient to evaluate the efficacy. In addition, the dosage form and dosage of curcumin used in each experiment are also different. Therefore, it is difficult to compare the effects of curcumin between different studies, and it is difficult to get a consistent conclusion [5].

///

On the other hand, curcumin is a pan-screening interfering compound, which makes it difficult for researchers to judge whether curcumin plays a role in a certain target.

The so-called pan-screening interfering compounds mean that they do not act on the target target but present a sharply confusing false positive result.

Real drugs can precisely act on specific protein binding sites, thus inhibiting or activating the function of protein. The "false positive compounds" are disguised as drug combinations, and smoke bombs are released in various screening studies. Moreover, curcumin does have a wide range of biological activities, just like an all-round sports fan who can win an excellent participation award in various competitions. Therefore, it is not a simple matter to judge whether curcumin has played a valuable role in some way and can be detected correctly [5].

With this explanation, it seems that curcumin is still far from being used as medicine, but there is no need to worry. The above problems are what scientists are trying to solve.

Last time, I made it clear that clinical studies show that taking curcumin up to 12g per day has no side effects, and the FDA also lists curcumin as a recognized safe food additive. We often eat curry, which is healthy and delicious. Isn’t it delicious? As a dietary supplement, curcumin products can also be eaten.

The following summarizes some kinds of turmeric derivatives in life and their uses [6]:

kind

character

use

Curcuma rhizome (intact)

Orange-brown rhizome (dry)

medicinal

Turmeric powder

Red and yellow powder, made by grinding dried rhizome.

Medicine, spices, dyes, dietary supplements

Turmeric resin

Brown viscous liquid, extracted from roots or leaves.

Medicinal, food colorants, dietary supplements

Ginger butter

Brown oil, extracted from roots or leaves.

Medicine, spices, dietary supplements

Curcumin

Orange-red crystalline powder, extracted and purified from turmeric powder.

Medicinal and dietary supplements

Once again, the content of this article is not used to persuade people to quit. We are just adhering to the consistent style, putting facts and being reasonable! Curry tastes good, so can curcumin ~

references

[1] Bernabé-Pineda M., Ram?rez-Silva M.a.T., Romero-Romo M., González-Vergara E., Rojas-Hernández A. Determination of acidity constants of curcumin in aqueous solution and apparent rate constant of its decomposition. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 2004; 60:1091–1097. doi: 10.1016/S1386-1425(03)00342-1.

[2] Priyadarsini KI. The chemistry of curcumin: from extraction to therapeutic agent. Molecules. 2014; 19(12):20091-20112. Published 2014 Dec 1. doi:10.3390/molecules191220091

[3] Zheng B, McClements DJ. Formulation of More Efficacious Curcumin Delivery Systems Using Colloid Science: Enhanced Solubility, Stability, and Bioavailability. Molecules. 2020; 25(12):2791. Published 2020 Jun 17. doi:10.3390/molecules25122791

[4] Xie Tao, Du Guanhua. The pain of Qualcomm’s quantitative screening —— Pan-active screening interfering compounds [J]. Journal of Pharmacy, 2015(08):925-930.

[5] Nelson KM, Dahlin JL, Bisson J, Graham J, Pauli GF, Walters MA. The Essential Medicinal Chemistry of Curcumin. J Med Chem. 2017; 60(5):1620-1637. doi:10.1021/acs.jmedchem.6b00975

[6] Li S., Yuan W., Deng G., Wang P., Yang P., Aggarwal B. B. Chemical composition and product quality control of turmeric (Curcuma longa L.) Pharmaceutical Crops. 2011; 2(1)

If you have any doubts, ideas, or problems in the field of anti-aging, welcome to discuss them in the comment area!

Original title: "Anti-cancer is short, life expectancy is insufficient, and the anti-aging" new star "curcumin is a complete scam? ! 》

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Statistical Bulletin of Tianjin National Economic and Social Development in 2018

Tianjin Bureau of Statistics National Bureau of Statistics Tianjin Survey Corps

  March 1, 2019

  In 2018, under the guidance of Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era, Tianjin thoroughly implemented the spirit of the 19th National Congress of the Communist Party of China and the Second and Third Plenary Sessions of the 19th Central Committee, took the important requirements of "three efforts" put forward by the General Secretary of the Supreme Leader as the key link, adhered to the general tone of striving for progress in stability, thoroughly implemented the new development concept, took the initiative to do a good job in stabilizing employment, finance, foreign trade, foreign investment and expectations. The overall economic operation has remained stable, structural optimization has been continuously promoted, quality and efficiency have been steadily improved, market vitality has been continuously enhanced, people’s livelihood has improved significantly, and a high-quality development trend is taking shape.

  I. Synthesis

  In 2018, the city’s gross domestic product (GDP) was 1,880.964 billion yuan, an increase of 3.6% over the previous year. Among them, the added value of the primary industry was 17.271 billion yuan, up by 0.1%; The added value of the secondary industry was 760.981 billion yuan, an increase of 1.0%; The added value of the tertiary industry was 1,102.712 billion yuan, an increase of 5.9%. The tertiary industrial structure is 0.9:40.5:58.6.

  The quality of fiscal revenue has improved significantly.The annual general public budget revenue was 210.619 billion yuan. Among them, the tax revenue was 162.484 billion yuan, accounting for 77.2% of the general public budget revenue, an increase of 7.7 percentage points over the previous year. From the perspective of main taxes, the value-added tax was 69.843 billion yuan, an increase of 6.7%; Enterprise income tax was 31.951 billion yuan, an increase of 3.1%; Personal income tax was 12.978 billion yuan, an increase of 11.4%. The annual general public budget expenditure was 310.453 billion yuan. Among them, social security and employment expenditure was 50.408 billion yuan, up by 9.7%; Education expenditure was 44.667 billion yuan, an increase of 3.3%; Medical and health expenditure was 19.255 billion yuan, an increase of 5.7%; Expenditure on housing security was 9.171 billion yuan, an increase of 43.1%.

  The annual task of supply-side structural reform was fully implemented.De-capacity has been solidly promoted. In the fourth quarter of 2018, the utilization rate of industrial capacity above designated size in the city was 78.5%, up by 1.4 percentage points over the same period of last year, crude steel output increased by 6.4%, down by 13.4 percentage points over the previous year, and pig iron output decreased by 0.5%. The effect of deleveraging was remarkable. At the end of 2018, the asset-liability ratio of industrial enterprises above designated size was 57.9%, down by 1.9 percentage points from the end of last year, which was the lowest level since 2013. The cost of enterprises has been gradually reduced, and a new batch of cost reduction policies and measures have been introduced. The introduced cost reduction policies and measures have reduced the burden on enterprises by about 60 billion yuan throughout the year. In 2018, the income cost of the main business of industrial enterprises above designated size was 84.01 yuan, a decrease of 0.91 yuan over the previous year.

  The private economy remains active.Firmly establish the concept of "industry first, entrepreneurs first", fully implement the "Tianjin Eight Articles" and 61 implementation rules, the business environment continues to improve, and market players continue to increase. In 2018, there were 221,100 newly registered market entities in the city, including 218,800 private market entities, accounting for 98.9% of the city’s total, with 599 newly registered daily. The development momentum in major areas is good. The added value of the city’s private economy was 855.176 billion yuan, up by 1.5%, accounting for 45.5% of the city’s economy. The industrial added value of private industrial enterprises above designated size increased by 2.5%, and the total industrial output value increased by 8.3%, which were 6.6 and 6.7 percentage points faster than the previous year, accounting for 22.8% and 31.3% of the city’s industry respectively. Private investment increased by 4.4%, 10 percentage points faster than that of the whole city. Among them, private investment in real estate development and operation increased by 30.5%, leasing and business services increased by 99.2%, electricity, heat, gas and water production and supply increased by 56.6%, and transportation, warehousing and postal services increased by 2.1%. The export of private enterprises increased by 42.0%, which was 33.4 percentage points faster than the city’s export, accounting for 32.7% of the city’s export.

  Consumer prices rose moderately.In 2018, the city’s consumer price rose by 2.0%, down 0.1 percentage point from the previous year. Among them, food prices rose by 3.4% and non-food prices rose by 1.7%; Consumer goods prices rose by 2.3% and service prices rose by 1.6%.  

  The price increase of industrial producers has dropped.In 2018, the ex-factory price of industrial producers in the city rose by 5.4%, down 3.0 percentage points from the previous year; The purchase price of industrial producers rose by 6.2%, down by 4.9 percentage points.

  Second, agriculture

  Agricultural production is basically stable.The total agricultural output value for the whole year was 39.100 billion yuan, down 0.2% from the previous year. Among them, the output value of planting industry was 18.775 billion yuan, down by 3.4%; The forestry output value was 1.273 billion yuan, an increase of 50.2%; The output value of animal husbandry was 9.645 billion yuan, down by 4.8%; The fishery output value was 8.04 billion yuan, an increase of 18.7%; The output value of agriculture, forestry, animal husbandry and fishery services was 1.367 billion yuan, an increase of 7.5%. The plan to revitalize Xiaozhan Rice was launched, and the supply of major "vegetable basket" products such as vegetables, meat, eggs and milk remained stable.

  Modern urban agriculture has developed rapidly.The strategic plan for rural revitalization in our city was issued, and the "six systems" of industrial development, reform and innovation, people’s livelihood security, environmental construction, rural governance and policy support were established. New formats such as pastoral complexes, modern agricultural industrial parks, and shared farms have been accelerated, and the number of demonstration bases for breeding applications of the Internet of Things has reached 800. Ten Sino-Israeli agricultural science and technology cooperation demonstration parks will be built, and 100 large-scale standardized facilities parks and 10 green recycling animal products production bases will be built. There are 182 leading rural enterprises at or above the municipal level, and 79 specialized villages with one village and one product. 150 beautiful villages have been built.

  III. Industry and Construction Industry

  In 2018, the city’s industrial added value was 696.271 billion yuan, an increase of 2.6% over the previous year; The added value of the construction industry was 66.338 billion yuan, down by 16.7%.

  Industrial production remained stable.The added value of industrial enterprises above designated size increased by 2.4% in the whole year, 0.1 percentage point faster than the previous year. In terms of economic types, the added value of state-owned enterprises increased by 1.0%, private enterprises increased by 2.5%, and foreign and Hong Kong, Macao and Taiwan businesses increased by 4.4%. In terms of three categories, the added value of mining industry decreased by 1.4%, manufacturing industry increased by 3.2%, and electricity, heat, gas and water production and supply industries increased by 5.4%. From the main industries, the added value of agricultural and sideline food processing industry increased by 19.1%, electrical machinery and equipment manufacturing industry increased by 18.5%, metal products industry increased by 18.3%, special equipment manufacturing industry increased by 12.6%, pharmaceutical manufacturing industry increased by 8.8%, automobile manufacturing industry increased by 7.1%, and oil, coal and other fuel processing industry increased by 2.0%.

  The efficiency of enterprises has increased rapidly.In the whole year, the main business income of industrial enterprises above designated size increased by 6.5%, 1.2 percentage points faster than the previous year, the total profit increased by 11.1%, and the profit rate of main business income was 6.8%, 0.4 percentage points higher than the previous year. Among them, the oil and gas mining industry, coal mining and washing industry, pharmaceutical manufacturing industry, tobacco products industry and food manufacturing industry have outstanding profitability, and the profit rate of main business income has reached double-digit level.

 

  Production in the construction industry continued to decline.The total output value of the construction industry in the whole year was 379.110 billion yuan, down by 11.1%. The building construction area of construction enterprises is 133.7988 million square meters, of which the newly started area is 42.4925 million square meters. By the end of the year, there were 988 general contracting and professional contracting construction enterprises with special, first-class and second-class qualifications in the city, an increase of 134 over the end of last year.

  Four, wholesale and retail and accommodation and catering

  In 2018, the added value of wholesale and retail in the city was 236.145 billion yuan, an increase of 0.8%; The added value of accommodation and catering industry was 32.794 billion yuan, up by 4.5%.

  The business market developed steadily.The annual sales of wholesale and retail commodities increased by 3.1%. The total retail sales of social consumer goods was 553.304 billion yuan, up by 1.7%. Among the commodities above designated size, the retail sales of petroleum and products increased by 10.8%, 6.8 percentage points faster than that of the previous year, driving the retail sales above designated size of the city to increase by 1.7 percentage points; Clothing, shoes, hats and knitted textiles increased by 10.5%; Furniture category increased by 6.1%; Grain, oil and food increased by 2.9%. There are 60 wholesale markets with a turnover of over 100 million yuan, with an annual turnover of 197 billion yuan.

  The mass catering market continues to be active.The annual turnover of accommodation and catering industry increased by 10.8%, maintaining double-digit growth. Among them, the turnover of accommodation and catering industry below designated size increased by 12.1%, which was 1.3 percentage points faster than that of the whole city; The turnover of fast food above designated size increased by 8.8%, and the turnover of catering and distribution services increased by 45.8%.

  V. Investment in fixed assets

  Investment in fixed assets declined slightly.In 2018, investment in fixed assets (excluding farmers) decreased by 5.6% compared with the previous year in comparable terms. In terms of industries, investment in the primary industry decreased by 9.1%; Investment in the secondary industry decreased by 6.3%, and investment in the tertiary industry decreased by 5.3%. Investment in manufacturing industry decreased by 22.0%, of which computer communication and other electronic equipment manufacturing industry increased by 11.2% and automobile manufacturing industry increased by 7.0%.

  In 2018, the city strictly implemented various national regulatory policies, and gradually established and improved a long-term mechanism for the development of the real estate market. The investment in real estate development increased by 8.6%. The sales area of commercial housing was 12,498,700 square meters, down by 15.7%, and the decline was 29.6 percentage points narrower than that of the previous year; Sales reached 200.662 billion yuan, down 11.7%, narrowing by 23.0 percentage points over the previous year.

  VI. Transportation, Posts and Telecommunications

  In 2018, the added value of transportation, warehousing and postal services in the city was 81.633 billion yuan, an increase of 3.1%.

  Transportation has developed steadily.The annual freight volume was 535.4807 million tons, an increase of 1.0% over the previous year. Among them, there are 347,111,400 tons of roads, 92,477,000 tons of railways and 82,609,400 tons of water transportation. The turnover of goods was 198.428 billion tons kilometers, an increase of 2.3%. Among them, there are 40.41 billion tons of highways, 24.502 billion tons of railways and 132.66 billion tons of waterways. Passenger traffic was 192 million, an increase of 0.3%; Passenger turnover was 55.349 billion person-kilometers, an increase of 4.9%. Port cargo throughput was 508 million tons, up by 1.4%; The container throughput was 16.0069 million TEUs, an increase of 6.2%. The airport passenger throughput was 23,591,400 passengers, an increase of 12.3%; The cargo and mail throughput was 258,700 tons, down by 3.6%. By the end of the year, the number of civilian cars in the city was 2,986,900, including 2,501,400 private cars; There are 1,920,200 civilian cars, including 1,738,800 private cars.

  The business volume of posts and telecommunications has doubled.The total postal and telecommunications business in the year was 85.105 billion yuan, up 1.1 times. Among them, the total telecommunications business was 73.571 billion yuan, up 1.4 times, 73.4 percentage points faster than the previous year; The total business volume of the postal industry was 11.534 billion yuan, an increase of 8.7%. By the end of the year, there were 16.485 million mobile phone users, an increase of 4.3%. There were 9.093 million Internet broadband access ports, an increase of 14.3%. There were 14.218 million mobile Internet users and 4.379 million fixed Internet users, up by 8.6% and 29% respectively.

  VII. Finance

  In 2018, the added value of the city’s financial industry was 196.689 billion yuan, an increase of 7.2%.

  The balance of financial deposits and loans maintained growth.By the end of the year, the balance of local and foreign currency deposits of financial institutions (including foreign capital) in the city was 3,098.317 billion yuan, an increase of 4.236 billion yuan and 0.1% over the beginning of the year. The balance of various loans was 3,408.490 billion yuan, an increase of 243.909 billion yuan or 7.9% over the beginning of the year.

  The securities trading market developed steadily.In 2018, there were 18 new domestic and overseas listed companies and New Third Board listed companies in the city, reaching a total of 259. At the end of the year, there were 5,167,800 securities accounts, an increase of 8.2% over the end of last year. The transaction volume of various securities in the whole year was 3,718.374 billion yuan, down by 14.6%. Among them, the stock trading volume was 1,766.173 billion yuan, down by 20.8%; The bond transaction volume was 1,693.048 billion yuan, down by 13.5%; The fund transaction volume was 252.6 billion yuan, an increase of 58.1%. The turnover in the futures market was 6,661.489 billion yuan, an increase of 10.2%.

  The insurance market developed steadily.The original insurance premium income for the whole year was 55.998 billion yuan, down 0.9% from the previous year. Among them, life insurance premium income was 41.554 billion yuan, down 1.9%; Property insurance premium income was 14.444 billion yuan, up by 2.0%. The annual compensation was 16.414 billion yuan, an increase of 5.7% over the previous year. Among them, personal insurance paid 8.375 billion yuan, an increase of 3.1%; Property insurance paid 8.039 billion yuan, up 8.5%. By the end of the year, there were 3,936 insurance institutions and 98,600 insurance employees in the city.

  Eight, development and opening up

  Investment promotion has been solidly promoted.In 2018, the city introduced a total of 3,339 domestic-funded projects, and the actual utilization of domestic capital was 265.706 billion yuan. 524 manufacturing projects were introduced, with a capital of 17.663 billion yuan, accounting for 6.6%; 2,625 service industry projects were introduced, with a capital of 241.436 billion yuan, accounting for 90.9%, of which the capital of leasing and business services and financial services increased by 64.2% and 32.2% respectively. There are 1,088 foreign-invested enterprises newly approved in the city, with an increase of 14.4%. The contracted foreign capital is 24.649 billion US dollars, and the actual direct utilization of foreign capital is 4.851 billion US dollars.

  Opening to the outside world has achieved positive results.Strengthen economic and trade cooperation with countries and regions along the "Belt and Road", build a two-way industrial cooperation base, continue to promote the construction of the expansion zone of China-Egypt Suez Economic and Trade Cooperation Zone, and make progress in the construction of advanced manufacturing industrial parks in China and Europe. In the whole year, 132 overseas enterprises and institutions were newly established, with Chinese investment of 2.105 billion US dollars. The newly signed contracts for foreign contracted projects amounted to US$ 4.45 billion, with a turnover of US$ 5.3 billion. By the end of the year, there were 16,900 foreign contracted projects and labor cooperation personnel.

  The growth rate of foreign trade exports increased.In 2018, the city’s foreign trade import and export totaled 807.701 billion yuan, an increase of 5.6%. Among them, imports were 486.985 billion yuan, an increase of 3.8%; Exports reached 320.716 billion yuan, an increase of 8.6%, an increase of 7.4 percentage points over the previous year. General trade exports reached 155.571 billion yuan, an increase of 8.3%, 4.6 percentage points faster than the previous year; The export of processing trade was 142.638 billion yuan, up 6.9%, 6.9 percentage points faster than the previous year. Exports to Russia and ASEAN along the Belt and Road increased by 60.5% and 23.0% respectively, while exports to the United States and the European Union increased by 7.2% and 2.0% respectively.

    Reform and innovation in the Pilot Free Trade Zone continued to deepen.90 reform tasks and two batches of 175 institutional innovations were basically completed. The "Deep Reform Plan" was approved and implemented by the central government, and 84 of the 128 tasks have been completed, taking the lead in implementing innovative policies such as enterprise business license with one address and multiple certificates, and foreign debt facilitation of financial leasing special purpose companies. The Pilot Free Trade Zone has accumulated 51,000 newly registered market entities, which is 2.2 times the sum of the previous years; In 2018, the actual direct utilization of foreign capital was 1.551 billion US dollars, accounting for 32% of the city. Financial leasing and parallel imported automobile business continue to maintain the national leading level.

  Tourism has developed rapidly.In the whole year, it received 1,983,100 inbound tourists, including 1,759,800 foreigners, and the foreign exchange income of inbound tourism was 1.11 billion US dollars. Received 227 million domestic tourists, an increase of 9.1% over the previous year; Domestic tourism revenue was 384.089 billion yuan, an increase of 16.7%. Residents of our city traveled abroad for 897,500 times, an increase of 85.1%. At the end of the year, there were 82 star-rated hotels and 104 scenic spots with Grade A and above in the city.

  Nine, Beijing-Tianjin-Hebei coordinated development

  The function of serving the non-capital and the construction of xiong’an new area have achieved remarkable results.Actively undertake the relief of Beijing’s non-capital functions, Binhai-Zhongguancun Science Park has registered 941 enterprises, and the construction of Beijing-Tianjin Cooperation Demonstration Zone, Baodi Beijing-Tianjin Zhongguancun Science and Technology City and Wuqing Beijing-Tianjin Industrial New City has been accelerated. The National Convention and Exhibition Center project has started construction, and a number of projects such as China Communications Construction Beijing-Tianjin-Hebei Regional Headquarters and China University of Nuclear Industry have signed contracts. Take the initiative to serve the construction and development of xiong’an new area, and speed up the implementation of eight aspects of the Tianjin-Hebei cooperation agreement. In the whole year, Beijing-Hebei enterprises invested 123.388 billion yuan in Tianjin, accounting for 46.4% of the actually utilized domestic capital in the city.

  Breakthroughs in key areas are progressing smoothly.Infrastructure coordination was accelerated, Jinxiong Intercity was included in the national plan, the construction of Jingbin and Jingtang railways was accelerated, the preliminary work of Tianjin-Beijing new airport connection line was accelerated, the Beijing-Qinhuangdao Expressway Hebei-Tianjin connection line was opened, the eastern section of Tianjin-Shijiazhuang Expressway was started, and the first branch line around the Bohai Sea between Tianjin Port and Caofeidian Port was opened. The restrictions on small and minibuses with Beijing licenses in Tianjin are managed in the same city, and the "one card" of Beijing-Tianjin-Hebei traffic covers all bus and subway lines. The Beijing-Tianjin-Hebei (Tianjin) Comprehensive Reform Experimental Zone for Inspection and Quarantine was put into operation. The total import and export volume of Tianjin Port was 1,384.604 billion yuan, up 9.2%, of which the proportion of goods from Beijing and Hebei reached 30.2%, up 0.4 percentage points over the previous year. Industrial docking cooperation continued to deepen, and projects such as Beijing-Tianjin-Hebei Big Data Collaborative Processing Center and Xiqing Electronic City Data Center were smoothly promoted. The joint prevention, control and treatment of ecological and environmental protection have been continuously strengthened, and the action plan for comprehensive control of air pollution in autumn and winter in 2018-2019 has been introduced, and the coordinated control of regional atmosphere, water and soil has been deepened.

  X. New Economy

  The growth of new industries has accelerated.In 2018, among the industries above designated size, the added value of high-tech industries (manufacturing) increased by 4.4%, 2.0 percentage points faster than that of the whole city, accounting for 13.3%; The added value of strategic emerging industries increased by 3.1%, accounting for 21.8%, an increase of 1.0 percentage points over the previous year. Among the service industries above designated size, the operating income of strategic emerging service industry, high-tech service industry and science and technology service industry increased by 9.2%, 11.9% and 12.2% respectively, and the profit margins reached 8.5%, 7.3% and 7.5% respectively.

  The output of new products is growing well.The output of new energy vehicles increased by 4.1 times, service robots and industrial robots increased by 94.3% and 20.0% respectively, and integrated circuit wafers, lithium-ion batteries, electronic components and computer machines increased by 44.1%, 23.7%, 22.8% and 12.4% respectively.

  New formats are booming."internet plus" promotes the development of online and offline integration. In 2018, the express delivery business volume was 576 million pieces, up by 14.7%. The layout of new retail has been accelerated, and new retail convenience stores such as JD.COM Convenience Store, Tmall Store, Suning Store, Convenience Bee Store, Wheat Store and JD.COM X Unmanned Supermarket have sprung up rapidly. New retail fresh supermarkets such as 7FRESH in JD.COM, G-Super in Greenland and Baoyan Daojia have settled down and opened, and the first JD.COM X Future Restaurant in China has opened its doors in Tianjin Eco-city.

  XI. Urban Construction and Public Utilities

  The function of urban carrier has been continuously improved.The construction of subway was accelerated, Metro Lines 5 and 6 were opened to traffic, the east extension line of Line 1 was tested, and Lilou and Shuanglin stations were put into trial operation. The number of subway lines in the city increased to six, with a total mileage of 220 kilometers. The urban traffic network has been continuously improved, 49 urban roads with a total area of 1.9 million square meters have been renovated, and main roads such as Glory Road have been opened to traffic, and 95 new bus lines have been optimized, making our city the first batch of national transit metropolis demonstration cities. In 2001, the number of public transport passengers was 1.505 billion, of which 408 million were rail transit passengers, up by 15.9%. Eight urban parks, such as Beining and Tianjin Bay, were newly built and upgraded, and Shuixi Park, the largest urban park in the city, was opened. Newly built and renovated 375 public toilets. By the end of the year, the city’s highway mileage was 16,257 kilometers, including 1,262 kilometers of expressways.

  The development of public utilities has achieved practical results.Complete the transformation of the old water-gas heating pipe network for 230 kilometers, implement the energy-saving transformation of existing residential buildings of 2.08 million square meters and the heating metering and energy-saving transformation of existing public buildings of 1.71 million square meters, and start the central heating ahead of schedule for the third consecutive year. The construction of sponge city and underground pipe gallery continued to advance, and the PPP project of sponge city in Jiefang South Road started. The electricity consumption of the whole society is 86.144 billion kWh, of which the domestic electricity consumption of urban and rural residents is 11.162 billion kWh.

  XII. Education, Science and Technology

  Education has developed steadily.112 kindergartens were newly built, rebuilt and expanded, and the third round of modernization standard construction of 300 compulsory education schools was completed. Our city became the first batch of pilot cities for comprehensive reform of "three-round education". By the end of the year, there were 56 ordinary colleges and universities, 92 secondary vocational education schools, 536 ordinary middle schools and 879 primary schools in the city. In the whole year, there were 24,800 graduate students, 68,100 students and 17,200 graduates. Ordinary colleges and universities enrolled 152,700 students, 523,300 students and 138,800 graduates. Secondary vocational education schools enrolled 34,500 students, 112,200 students and 37,700 graduates. Ordinary middle schools enrolled 146,100 students, 440,100 students and 129,400 graduates. There are 127,300 primary school students, 673,200 students and 98,900 graduates. There are 2,223 kindergartens with 262,900 children.

  The innovation-driven strategy was implemented in depth.Successfully held the second World Intelligence Conference. Comprehensive innovation and reform will be deepened, national independent innovation demonstration zones will be built with high standards, a number of advanced manufacturing industry technology research institutes will be accelerated, and the construction of high-end think tanks such as China Engineering Science and Technology Development Strategy Research Institute and China New Generation Artificial Intelligence Development Strategy Research Institute will be promoted. Eight scientific and technological achievements in the city won the national science and technology awards, including one international cooperation award, one natural invention award and six scientific and technological progress awards. There are 2,331 municipal scientific and technological achievements registered, of which 94 belong to the international leading level and 262 reach the international advanced level. The prototype of "Tianhe-3" was successfully developed, and the 12-inch semiconductor silicon single crystal broke the international monopoly, and the diving depth of the underwater glider reached a new high. There are 5038 national high-tech enterprises, 55 leading enterprises in science and technology, and 279 new municipal "killer" and key new products. Start the construction of municipal technology innovation centers, newly put on record 25 municipal innovation spaces, and newly identified 24 municipal engineering technology research centers and 8 municipal science and technology business incubators. 99,000 patent applications were accepted throughout the year; There were 54,700 patents authorized, including 5,626 invention patents; At the end of the year, there were 168,900 valid patents, including 32,100 invention patents. At the end of the year, there were 13 national key laboratories, 12 national engineering (technology) research centers and 61 national enterprise technology centers in the city. In 2001, 11,315 technical contracts were signed, with a contract turnover of 72.5 billion yuan, an increase of 10.2%;The technology transaction volume was 55.3 billion yuan, an increase of 11.3%.

  The pace of talent introduction has obviously accelerated.The action plan of "Haihe Talents" introduced 133,000 talents, including 47,000 skilled and qualified talents, and a group of top leading talents and high-level talents in urgent need gathered in Tianjin. There are 37 academicians in Tianjin, 10 new postdoctoral workstations, 339 postdoctoral mobile stations and workstations at the end of the year, and 394 new postdoctoral fellows.

  XIII. Health, Culture and Sports

  The level of public health services continued to improve.The pattern of graded diagnosis and treatment has basically taken shape. All secondary and tertiary hospitals and grass-roots medical and health institutions in the city have participated in the construction of medical associations and set up 10 professional specialist medical associations. The "Tianjin Health Sports Cloud Platform" was launched to dynamically monitor the physical condition of citizens. The contract service of family doctors was further improved, with 43,000 disabled elderly people signing contracts and 225,000 home visits. By the end of the year, there were 5,686 health institutions in the city. There are 566 hospitals and health centers. There are 68,200 beds in health institutions, including 64,600 in hospitals and health centers. There are 104,400 health technicians, including 43,000 licensed (assistant) doctors and 39,400 registered nurses.

  Cultural undertakings have developed rapidly.Vigorously implement the project of benefiting the people through culture, hold the third citizens’ culture and art festival, and issue more than 20,000 citizens’ lifelong learning cards. A series of cultural activities were launched to celebrate the 40th anniversary of reform and opening up, and the TV series "Changed the World" was broadcasted nationwide. There are 100 district-level public libraries, 900 grass-roots service points, 464 exhibitions and 8.99 million visitors. By the end of the year, there were 103 performing arts groups, 17 cultural centers, 65 museums, 29 public libraries and 244 comprehensive cultural stations in towns and villages. There are 101 cinemas in the city, with 684 screens and more than 100,000 seats. In the whole year, the box office revenue of urban movies was 882 million yuan (including service fees), with more than 1.3 million screenings and more than 25 million people watching movies. In 2001, 92 million books, 26.92 million magazines and 321 million newspapers were published.

  Excellent achievements in sports.In 2018, our athletes won 35 gold medals in domestic high-level competitions and 14 gold medals in international high-level competitions, including 7 gold medals, 6 silver medals and 3 bronze medals in the Asian Games in Jakarta. Tianjin women’s volleyball team won the national league championship for the 11th time. The national fitness program is rich and active, with 50,000 sports Huimin cards issued, and more than 1,200 fitness parks, fitness squares and sports parks built and renovated, and the 14th Tianjin Games was successfully held.

  XIV. Population, Employment and People’s Life

  The resident population increased slightly.By the end of 2018, the permanent population of the city was 15.596 million, an increase of 27,300 over the end of last year. Among them, there are 4,990,100 migrants, accounting for 32.0% of the city’s permanent population. Among the permanent residents, the urban population is 12,968,100, and the urbanization rate is 83.15%. The birth rate of permanent residents is 6.67‰, the death rate is 5.42‰, and the natural growth rate is 1.25‰. At the end of the year, the registered population of the city was 10,816,300.

  The quality of employment has been further improved.We will implement 22 policies to promote college students’ entrepreneurship and employment, properly resettle and resolve employees of enterprises with excess capacity, and ensure that at least one person from zero-employment families and low-income families will achieve employment. The city will create 490,000 new jobs, and the registered urban unemployment rate will be 3.5% at the end of the year. By the end of the year, there were 8,965,600 employed people in the whole society. Among them, the number of migrant workers was 3,597,800, an increase of 16,000; The urban employed population was 7,142,100, an increase of 41,000. There are 600,700 employees in the primary industry, 2,850,200 employees in the secondary industry and 5,514,700 employees in the tertiary industry.

  Residents’ income and expenditure grew steadily.Implement 17 measures to increase income. The per capita disposable income of residents in the city was 39,506 yuan, an increase of 6.7%. According to the place of permanent residence, the per capita disposable income of urban residents was 42,976 yuan, an increase of 6.7%; The per capita disposable income of rural residents was 23,065 yuan, an increase of 6.0%. The per capita consumption expenditure of residents in the city was 29,903 yuan, up by 7.4%, of which the expenditure on education, culture and entertainment, transportation and communication, and medical care increased by 18.4%, 14.3% and 12.0% respectively.

  XV. Social Security and Social Assistance

  The social security system has been continuously improved.Improve the unemployment insurance benefits standard, the basic pension subsidy standard for urban and rural residents, and the living allowance standard for the elderly in urban and rural areas, promote the expansion of medical insurance, and substantially increase the reimbursement limit for outpatient and emergency services of basic medical insurance. By the end of the year, the number of people participating in basic medical insurance in the city was 11,167,200, an increase of 282,700 over the end of last year; The number of people participating in basic old-age insurance was 8,443,100, an increase of 324,900; The number of people participating in industrial injury insurance for urban workers was 3,985,200, an increase of 31,900; 3,234,400 people participated in unemployment insurance for urban workers, an increase of 121,400; The number of people participating in maternity insurance for urban workers was 3,304,200, an increase of 334,700. 20,000 sets of affordable housing were built, 570,000 square meters of shantytown renovation was completed, and 1,300 blocks and 40 million square meters of old residential areas and distant housing were upgraded, benefiting 650,000 families. There are 5,000 dilapidated houses in rural areas, and a total of 30,000 poor peasant families live in peace and warmth.

  The level of social assistance services continued to improve.We will improve the standards of urban and rural subsistence allowances, assistance to low-income families, special hardship support, and pensions for special care recipients, and build 30 day care centers for the elderly, covering more than 95% of old-age care institutions with the combination of medical care and nursing. By the end of the year, there were 1,301 day care service centers (stations) for the elderly in the city with 10,000 beds; There are 142,500 low-income residents in the city, 12 rescue stations and 7,656 rescue services. Social service organizations providing accommodation have 53,300 beds, and various service organizations adopted 31,800 people at the end of the year. In the whole year, 299,600 people participated in the basic medical insurance, 726,600 people received direct medical assistance, and the medical assistance fund expenditure was 646 million yuan. Subsidies for water, electricity and gas were distributed to 62,000 eligible disabled people.

  Sixteen, poverty alleviation and ecological environmental protection

  Accurate poverty alleviation has been further promoted.Strengthen the city’s difficult villages to help each other, arrange 1,000 difficult villages to develop economic support funds of 1.12 billion yuan, and distribute rental subsidies to 148,000 low-and middle-income families with housing difficulties. We formulated and implemented a three-year action plan to promote poverty alleviation cooperation and counterpart support between the east and the west in our city, arranged a budget of 2.57 billion yuan for counterpart support to provinces and cities in full, solidly promoted counterpart assistance to 82 counties (cities, districts), implemented 842 assistance projects, selected more than 1,100 cadres and talents, helped 20,000 poor people to achieve employment and income increase, and helped 10 poor counties to take the lead in getting rid of poverty.

  Pollution prevention and control has achieved remarkable results.The first batch of red lines for ecological protection in China was delineated, and a red line was realized to control the ecological space. Actively implement environmental protection work such as coal to electricity and coal to gas, with a total investment of more than 30 billion yuan, involving 1.213 million households. Between the central city and Binhai New Area, 736 square kilometers of "double cities with green" ecological barrier is planned to be built, and 7,400 mu of greening task in the starting area is completed. The city added 380,000 mu of afforestation and 15 million square meters of newly-built green space. In-depth implementation of the "1+4" plan for wetland nature reserves will comprehensively upgrade and protect 875 square kilometers of wetlands such as Qilihai, Beidagang, Tuanbo and Dahuangbao. The air quality has obviously improved. The average annual concentration of PM2.5 in the city is 52 μ g/m3, down by 16.1% compared with the previous year, and the number of days of heavy pollution has decreased by 13 days compared with the previous year, the best level since monitoring in 2013. The proportion of surface water inferior to Grade V decreased by 15 percentage points over the previous year.

Note: 1. All data in this bulletin are preliminary statistics.

  2. The absolute figures of the city’s GDP and the added value of various industries are calculated at current prices, and the growth rate is calculated at constant prices. According to the results of the third national agricultural census, the historical data of the city’s GDP and the proportion of added value of the three industries were revised.

  3. Industrial enterprises above designated size refer to all corporate industrial enterprises with annual main business income of 20 million yuan or more.

  4. Service enterprises above designated size refer to transportation, warehousing and postal services, information transmission, software and information technology services, real estate (excluding real estate development and operation), leasing and business services, scientific research and technical services, water conservancy, environment and public facilities management, education, health and social work legal entities with annual business income of 10 million yuan or more; Residents’ service, repair and other service industries, cultural, sports and entertainment legal entities with annual business income of 5 million yuan or more, or employees of 50 or more at the end of the year.

  5. Wholesale enterprises above designated size refer to wholesale enterprises with annual main business income of 20 million yuan or more; Retail enterprises above designated size refer to retail enterprises with annual main business income of 5 million yuan or more; Accommodation and catering enterprises above designated size refer to accommodation and catering enterprises with annual main business income of 2 million yuan or more.

  6. According to the results of the third national agricultural census and relevant regulations, the base of total retail sales of social consumer goods in 2017 will be revised, and the growth rate in 2018 will be calculated according to comparable caliber.

  7. The statistical scope of fixed assets investment (excluding farmers) covers the investment in fixed assets projects and all real estate development projects with a planned total investment of 5 million yuan or more.

  8. The total telecom business is calculated at 2015 prices.

  9. The total business volume of the postal industry is calculated at 2010 prices.

  Source:

  The financial data in this bulletin comes from Tianjin Finance Bureau; The registration data of market entities comes from Tianjin Municipal Market Supervision and Management Committee; Transportation data comes from Tianjin Transportation Committee; Motor vehicle data comes from Tianjin Public Security Traffic Management Bureau; Postal data comes from Tianjin Postal Administration; Telecom data comes from Tianjin Communications Administration; Culture and tourism data come from Tianjin Culture and Tourism Bureau; Data of deposits and loans come from Tianjin Branch of China People’s Bank; The data of listed companies come from Tianjin Financial Work Bureau; Securities and futures data come from Tianjin Supervision Bureau of China Securities Regulatory Commission; Insurance data comes from Tianjin Supervision Bureau of Bank of China Insurance Regulatory Commission; Data on the utilization of foreign capital, overseas investment, foreign contracted projects and foreign labor cooperation come from Tianjin Municipal Bureau of Commerce. Import and export data from Tianjin Customs; Using domestic data from Tianjin Municipal People’s Government Cooperation and Exchange Office; Electricity consumption data comes from Tianjin Electric Power Company; Education data comes from Tianjin Education Commission; Scientific and technological innovation data comes from Tianjin Science and Technology Bureau; Patent data comes from Tianjin Intellectual Property Office; The data of talents, new employment and social security come from Tianjin Human Resources and Social Security Bureau. Medical insurance data comes from Tianjin Medical Security Bureau; Medical and health data come from Tianjin Health and Wellness Committee; Sports data comes from Tianjin Sports Bureau; The data of registered population comes from Tianjin Public Security Bureau; The data of social assistance service comes from Tianjin Civil Affairs Bureau; Environmental protection data comes from Tianjin Ecological Environment Bureau; Other data come from Tianjin Municipal Bureau of Statistics and Tianjin Investigation Corps of National Bureau of Statistics.

  

Learn from the past and learn from the past, follow the general secretary to learn history, feel the charm of Tianhan and inherit Chinese civilization.

  Hanzhong City, Shaanxi Province, is one of the birthplaces of human civilization. On July 29th, General Secretary of the Supreme Leader visited Hanzhong City, visited the exhibition of historical relics in Hanzhong Museum, and learned about the historical culture and cultural relics protection in Hanzhong. He pointed out that it is necessary to give full play to the important role of museums in protecting, inheriting, researching and displaying human civilization, protect the Chinese context, make cultural relics alive and expand the influence of Chinese culture.

  Learn from the past and learn history with the general secretary. Today, I walked into Hanzhong City to feel the charm of Tianhan and inherit Chinese civilization.

  Chinese cornucopia, birthplace of Han family

  Hanzhong City is located in the southwest of Shaanxi Province, bordering on Sichuan Province. It is named after the Hanshui River flows through this place, and it was also called "Tianhan" in ancient times.

△ Cultural relics unearthed in Hanzhong area (photographed by CCTV reporter Cheng Cheng)

  As early as the Paleolithic Age, there were primitive ancestors in Hanzhong. A large number of historical relics, such as stone tools and pottery, have been unearthed in the local Longgang Temple site and Mang Cave site, which proves the civilization and glory of Hanzhong.

  In the Xia Dynasty, the Youbao family, south of the Qinling Mountains, established a praise country in Hanzhong and became a member of early China. Since then, Hanzhong has opened a splendid civilization of Xia, Shang and Zhou dynasties.

  After the demise of the Qin Dynasty, Liu Bang took Hanzhong as his birthplace and achieved the inheritance of the Han family for more than 400 years. Han dynasty, Han nationality, Han nationality and Chinese have come down in one continuous line to this day, forming a splendid Chinese culture.

  "Every brick and stone records the vicissitudes of history." Hanzhong’s historical remains, such as worship altar, ancient Hantai, Yinmachi, Baoxie plank road and cliff stone carvings, silently tell people the endless life of Chinese civilization.

  Praise the oblique plank road for crossing the Millennium.

  The Hanzhong Museum visited by General Secretary of the Supreme Leader is a community museum based on the "Three Sites of the Western Han Dynasty". Among them, Guhantai was once the palace site where Hanwang Liu Bang had been stationed. There is not only the Wangjiang Tower, which enjoys the scenery of Qin and Shu at a glance, but also the famous ancient plank road at home and abroad.

△ Wangjianglou, located in Hanzhong Museum (photographed by CCTV reporter Cheng Cheng)

△ Stone carvings of Hanzhong Museum (photographed by CCTV reporter Cheng Cheng)

  "It’s hard to get through the road, but it’s hard to get into the sky!" In order to cross the Qinling-Bashan Mountains, ancient ancestors made holes in the cliff where they passed, inserted beams, laid boards and built plank roads.

  Hanzhong is a transportation hub connecting Bashu and Chang ‘an in ancient times. There are seven plank roads in the territory, which is known as the "hometown of plank roads". Among them, Baoxie ancient plank road has the earliest opening time, the largest construction scale and the longest use time, and is called "the crown of Shu Road".

△ Schematic diagram of Qin-Shu ancient road (photographed by CCTV reporter Li Bing)

  As a traffic artery connecting the Central Plains and Southwest China in ancient times, the plank road in Hanzhong promoted regional economic prosperity and cultural exchanges, showed the spirit of the ancients to open up the road to Xinjiang and forge ahead, and left behind historical allusions such as "building the plank road in an open way, hiding the darkness".

  Shimen yunhui national treasure

  At the southern end of the ancient plank road in Baoxie, there is a manually dug tunnel named "Shimen". Shimen Tunnel was built by "fire and water excitation" in Yongping period of the Eastern Han Dynasty, and it is also the earliest manually dug tunnel in the world.

  After the opening of Shimen Tunnel, there was a constant stream of officials, businessmen and literati in the past, leaving many inscriptions on the cliffs inside and outside Shimen. Among them, thirteen stone carvings are particularly precious, and they are called "Thirteen Stone Gates". In the sixties and seventies of last century, due to the construction of water conservancy, the "Shimen Thirteen Products" was chiseled and moved to Hanzhong Museum, and it has been restored and displayed to this day.

△ "Shimen" Cliff rubbings (partial)

  "Shimen Yunhui, jumping out of the cliff treasure of the book world; Fortunately in Han Dynasty, there is still priceless history. " "Thirteen Classics of Shimen" is not only an important document in the history of transportation, water conservancy and science and technology in ancient China, but also of great significance to the study of the evolution of ancient Chinese characters and the development of calligraphy art.

  Between square inches, a thousand years at a glance. From the "light of ancient Shu" in Sanxingdui Museum to the "charm of heavenly Han" in Hanzhong Museum, we can see the profoundness and long history of Chinese civilization.

  As General Secretary of the Supreme Leader said, "A museum is a big school." Inheriting Chinese civilization and protecting cultural roots, this "big school" shoulders a sacred mission.

  Producer: Shen Yong Zhao Xuehua Gong Xuehui

  Chief writer Liu Huimin

  Reporter Li Bing Cheng Cheng

  Broadcast Li Chun

  Audio production Liu Yifei

  Visual sense

COVID-19 vaccine stopped production, where can we fight? Is it necessary to vaccinate?

Source: Thumb worm

On January 10th, Kexing COVID-19 vaccine was exposed and stopped production, which caused a heated discussion. On January 11th, clover biology also indicated that the demand for vaccines based on COVID-19 is relatively low at home and abroad, and the resource input for COVID-19 business will be adjusted according to market changes.

The First Financial Reporter learned from some community health service centers in Shanghai that COVID-19 vaccine can still be vaccinated at present, but the demand for COVID-19 vaccine has really decreased recently.

The First Financial Reporter then inquired about Shanghai Health Cloud’s appointment for vaccination in COVID-19, and found that Beijing Kexing COVID-19 vaccine is still available in most community health service centers and vaccination sites. Other vaccines also include products of many companies, such as Chengdu Wesker, Shenzhou Cell, Unacon, Zhifeilong Koma, Livzon Bio, Kangxinuo (inhalation), Kangxinuo (injection), Beijing Bio, Wuhan Bio and Shenzhen Kangtai.

According to the analysis of some insiders, there are now more than a dozen COVID-19 vaccine products on the market, and the market may enter the stage of "destocking". Closing some production lines is also a measure to adjust the relationship between supply and demand. "The supply of vaccines is certainly guaranteed, as long as new COVID-19 mutants continue to appear." A related person told the First Financial Reporter.

On the other hand, because there are many choices of vaccines in COVID-19 at present, vaccines against new Covid-19 mutants and COVID-19 vaccines with new technical routes may be more popular.

Regarding whether COVID-19 vaccine should be vaccinated, Wei Yuquan, academician of China Academy of Sciences, director of the State Key Laboratory of Biotherapy in west china hospital and director of the Cancer Center, said in an interview with the media that the relevant state departments are vigorously promoting the listing of XBB COVID-19 vaccine.

Before New Year’s Day in 2024, the National Bureau for Disease Control and Prevention issued a notice clearly stressing that all localities should vigorously promote the vaccination of Covid-19 vaccine containing XBB mutant antigen, and guide severe and high-risk people to actively vaccinate. It is necessary to standardize vaccination and ensure vaccination safety. Comprehensively improve the accessibility of vaccination services during holidays, so as to facilitate the people to vaccinate nearby.

In June, 2023, the recombinant trivalent Covid-19 trimer protein vaccine from Chengdu Wesker was put into emergency use in some areas. The inoculation amount of westcott vaccine has not been officially disclosed, but according to the internal understanding of the company by the First Financial Reporter, the vaccination has reached hundreds of thousands of doses.

According to the first financial reporter, the vaccination amount of the vaccine is not large. Wei Yuquan said that at present, the new XBB COVID-19 vaccine is free of charge, and it is available for disease control in all parts of the country. People who need to be vaccinated can consult the nearest CDC or vaccination clinic for vaccination arrangements.

The decreasing demand for vaccines in COVID-19 has become a global trend. American vaccine manufacturers Moderna and Pfizer, and their German partner BioNTech, both lowered their revenue expectations due to the declining demand for vaccines in COVID-19. BioNTech predicts that the revenue in 2024 will be about 3 billion euros, lower than the 4 billion to 5 billion euros in 2023; Moderna’s vaccine sales in COVID-19 dropped by two-thirds year-on-year in 2023, but it still reached $6.7 billion. COVID-19 vaccine is the only profitable product of BioNTech and Moderna.

The First Financial Reporter learned that Moderna is also considering introducing COVID-19 vaccine against XBB mutant into China production base, but the demand for COVID-19 vaccine in China is a major concern of the company.

However, experts stressed that Covid-19 has not disappeared, and it is still mutating, and the best way to protect vulnerable people is still vaccination. On January 10th, COVID-19 infection data released by CDC website showed that in December, 2023, there were 88 severe cases and 11 deaths in COVID-19.

Globally, according to the data of the US Centers for Disease Control and Prevention, JN.1 mutant has accounted for about 62% of the total number of COVID-19 infections in the United States and has become the mainstream. The current level of Covid-19 infection in the United States has reached the second highest level since the outbreak of COVID-19.

On January 10th, WHO Director-General Tan Desai said that compared with November 2023, the number of hospitalized patients infected with Covid-19 increased by 42% in December, and the number of patients receiving intensive care increased by 62%. Although the COVID-19 epidemic no longer constitutes a "public health emergency of international concern", Covid-19 is still spreading, mutating and taking lives.

"The epidemic level in China is low, but it is affected by international epidemic strains and imported cases in the future. It is not excluded that JN.1 mutant will become the dominant epidemic strain in China." Peng Zhibin, director of the Respiratory Infectious Diseases Department of Infectious Diseases Management Office of China CDC, said at the previous press conference.


Dr. Night: Morbius draws attention to Master Leto joining Marvel Comics.

Morbius and Spider-Man are in the same box.


1905 movie network news Recently, a dark superhero movie adapted from Marvel comics.Dr. Night: MorbiusAfter the release of the new preview, the fans’ enthusiasm was instantly ignited. The superhero that has never been seen before in the Marvel universe attracted countless eyes, and the complex heart that is also evil, good and evil is difficult to distinguish, and the unique super power has triggered heated discussions among countless netizens. The appearance of Spider-Man’s arch-rival vulture, and Morbius’s self-proclaimed "venom" are even more surprise gift. "Dr. Night: Morbius" has created a box office of 14 billion US dollars.《Spider-Man: Far From Home》andVenomThe gold medal production teams of two super-popular film series made great efforts to build, and the unprecedented role of Marvel Comics on the big screen shocked the audience. Famous directorDaniel Espinosa(Alien awakening) directed,Jared Joseph Leto(Blade runner 2049Dallas Buyers Club.Starring, will be released on the global big screen from January 19, 2022.


Dr. Night appeared on the scene and attracted a hot discussion on the whole network.  

Hidden egg elements are surprising.


After the release of the new preview of "Doctor Night: Morbius", netizens were attracted by the new dark superhero played by Oscar winner Jared Joseph Leto, saying that "super powers are so cool". As a superhero character never seen before in the Marvel universe, Morbius’s complex personality of being both righteous and evil is extremely prominent, which has triggered a heated discussion among netizens about whether Morbius is a superhero or a super villain. The bat-like echolocation ability and unique magical skills such as gliding and teleporting have increased people’s curiosity about Morbius. How many unknown surprises there are in this "Dr. Night" who is both good and evil, let us wait and see!


"Dr. Night" Morbius


The most surprising thing is that there are many Spider-Man-related egg elements hidden in this notice, which has aroused the enthusiasm of netizens to play with stalks crazily. Among them, Spider-Man graffiti and the villain vulture, which had been exposed before, reappeared, but the Horn Daily in Morbius’s hand hides another mystery, which seems to hide eggs closely related to Spider-Man. At the end of the preview, Morbius teased himself as "I am the venom" after subduing a gangster with a knife, which aroused everyone’s infinite speculation and excited all fans, making people look forward to the arrival of "Dr. Night" Morbius!


Dr. Night appeared.


Master Leto’s premiere of Marvel Comics was praised by netizens. 

"Spider-Man" and "Venom" gold medal team escorted.


Dr. Night: Morbius tells the tortuous story of Spider-Man’s arch-rival Morbius from a disabled teenager suffering from blood diseases to a dark hero in Marvel Comics, and officially reveals the origin of Morbius, the most alternative dark superhero in Marvel universe. Jared Joseph Leto, who won the Oscar for Best Supporting Actor for Dallas Buyers Club, starred in the Marvel superhero movie for the first time. His gloomy and mysterious actor image is in perfect harmony with Morbius’s characteristics of being both good and evil. In the preview, Leto perfectly presents Dr. Morbius’s weak state when he was terminally ill and his strong state after transformation. The obvious figure change is particularly noticeable. Netizens have said that "this figure management is too powerful" and "Master Leto’s eyes are absolutely perfect", which makes people look forward to the film!


Morbius suffers from disease.


As the biggest Marvel superhero movie in 2022, The Night Doctor: Morbius was created by the gold medal production team of Spider-Man: Heroic Expedition and Venom, which created a total box office of 14 billion dollars, and will once again present a wonderful superhero blockbuster shocking feeling. Directed by the famous director daniel espinosa (Alien Awakening), Jared Joseph Leto (Blade Runner 2049), the Oscar winner, co-starred with famous Hollywood actors such as Adria Arjona (Pacific Rim: Thunder reappears), matt smith (Star Wars 9: The Rise of Skywalker), Jared Harris (Spy League) and tyrese gibson (Fast and Furious 8). On January 19, 2022, it was released on the global big screen.

Overall Promotion and Intensive Construction of IPv6 Transformation of Shanghai Municipal Government Website —— A Case Study of IPv6 Scale Deployment and Application in Shanghai Big Data Center

I. Implementation Background and Objectives

According to the requirements of the Action Plan for Promoting the Scale Deployment of the Sixth Edition of Internet Protocol (IPv6) issued by the Central Office and the State Council, the Notice of the General Office of the State Council on Printing and Distributing the Main Points of Government Affairs Disclosure in 2018 (Guo Ban Fa [2018] No.23), and the Notice of the General Office of the State Council on Printing and Distributing the Pilot Work Plan for Intensive Government Websites (Guo Ban Han [2018] No.71), Shanghai Big Data Center carried out the IPv6 upgrade and transformation of the whole station. At the same time, combined with the intensive platform construction of government websites, it organized and coordinated the websites of 16 district governments and 43 municipal government departments to realize IPv6 access and transformation simultaneously.

Second, the work situation

(a) to complete the "China Shanghai" portal IPv6 upgrade.

In 2018, based on the previous investigation, the Municipal Big Data Center made a work plan for upgrading and transforming the IPv6 portal of China Shanghai, and actively and steadily promoted related work in strict accordance with the work requirements.

The first is to clarify the subject of responsibility.The "China Shanghai" portal is hosted by the General Office of Shanghai Municipal People’s Government and undertaken by the Municipal Big Data Center. According to the job functions, the City Big Data Center is the main body responsible for the IPv6 deployment and transformation of "China Shanghai" portal website, responsible for implementing the work requirements and coordinating with other relevant departments to promote the IPv6 transformation of "China Shanghai".

The second is to clarify the status quo of the website.In July 2018, all the portals of "China Shanghai" were moved to the government cloud platform of the whole city, and the government cloud platform provided the network and equipment layer infrastructure in a unified way.

The third is to determine the work plan.After research and comparison, it is decided to use the firewall equipment exported from the network side, and use NAT64 protocol to realize the initiative connection of IPv4 network to access IPv6 network.

Figure 1: Business Access Process

NAT64 is a stateful network address and protocol conversion technology, which can realize the address and protocol conversion between IPv6 and IPv4 under TCP, UDP and ICMP protocols. This scheme can directly support IPv6 connection access without affecting the normal operation of the original business. The advantage is that the internal transformation of the data center is small, and it can be launched quickly, thus solving the problem of "skylight" on the page caused by external links.

Figure 2: Network deployment scenarios of 2:NAT64 and DNS64.

The Internet address of "China Shanghai" portal website is bound with the internal load-balancing address, so this time it will be realized by configuring NAT conversion from IPv6 address to IPv4 load-balancing address; This IPv6 address translation configuration is to add an IPv6 address entry on the original basis, without affecting the normal operation of the original IPv4 address.

At the end of 2018, we verified the connectivity, stability and IPv6 network effectiveness of the "China Shanghai" portal website one by one, and achieved the expected results.

(two) actively promote the city’s government website IPv6 upgrade.

The IPv6 transformation of Shanghai municipal government website needs the cooperation of many government departments and manufacturers, and it is difficult to coordinate and solve many tasks such as optical fiber circuit and political cloud network configuration, server networking and domain name resolution.

Since 2019, Shanghai has written the work requirements related to the IPv6 transformation of government websites into the "Annual Work Points of Government Affairs Openness" for two consecutive years. At the same time, according to the Notice of the General Office of Shanghai Municipal People’s Government on Printing and Distributing the Work Plan for the Construction of Intensive Platform of Shanghai Municipal Government Website (Hu Fu Ban [2019] No.9), we will deploy and promote the IPv6 transformation work together with the intensive work of government websites.

The website architecture of Shanghai municipal government is the interconnection of two platforms in urban areas, the websites of municipal departments are connected to the intensive platform of municipal government websites, and the network and equipment layer infrastructure is provided by the municipal government cloud platform. The 16 district-level platforms are the portal websites of all districts, which are transformed by the government cloud platforms of all districts.

The first is to complete the transformation of IPv6, an intensive platform for government websites.The transformation scope includes the portal website of the municipal government and the websites of 43 government departments. The municipal government cloud platform provides IPv6 addresses for the export of each website, and the municipal big data center applies for domain names for analysis.

Figure 3: IPv6 detection results

The second is to complete the IPv6 address transformation of cloud shield security protection service.The website authorities coordinate and promote Yundun technology providers to provide solutions, and apply for domain name resolution to Shanghai Big Data Center. At present, the websites of four departments using Yundun have all completed the IPv6 address transformation.

The third is to urge all commissions and bureaus to complete the IPv6 transformation of website dynamic link.Because most of the dynamic link backstage is developed and operated by the commissions, the IPv6 transformation of the website except the intensive part needs to be coordinated by the commissions. At present, most of the links have been transformed, and the IPv6 accessibility rate of the websites of various commissions and bureaus is basically above 90%.

The fourth is to complete the IPv6 address transformation of the portal website of the district government.The competent authorities of the portal websites of each district government formulated and implemented the upgrading scheme of the portal websites of this district government, and all 16 districts chose the cloud conversion service scheme to complete the IPv6 transformation.

Third, the effectiveness of the work

After intensive transformation, the use of IP in government websites has also changed from "multiple sites at one site" to "multiple sites at one site", and unified domain name resolution has been used to reduce the occupation of resources and greatly improve the efficiency of IPv6 upgrading.

At the end of 2020, the General Office of the State Council conducted a spot check on the IPv6 transformation of the national government websites. The websites of "China Shanghai" and 16 district governments all passed the retest, and the pass rate of the second and third level links exceeded 90%.

Fourth, work highlights

(1) Overall planning and unified deployment.The IPv6 transformation of government websites is a systematic project. From intensive integration to IPv6 transformation and deployment, it involves many contents, manufacturers and technical teams, and needs support from all sides. Shanghai Big Data Center actively cooperates with the general office of the municipal government to strengthen overall coordination and do a good job of communication and connection with technical support, construction trustees and network operators. After the transformation of IPv6, users of both IPv4 and IPv6 protocols can access it normally, so that government websites have many functions and services, and their normal use and access will not be affected.

(2) Intensive construction and simultaneous advancement.Shanghai Big Data Center reused the experience of "China Shanghai" IPv6 upgrade in the construction of intensive platform, and accelerated the deployment of IPv6 after relying on the intensive platform to solve most of the "external chain" problems. In 2019, relying on the intensive platform, it completed the IPv6 transformation of the city’s government websites in a unified way, and really achieved resource intensive.

(three) supervision and inspection to ensure the effectiveness.According to the Inspection Index of Government Websites and Government Affairs New Media and the Annual Assessment Index of Government Websites and Government Affairs New Media Supervision formulated by the General Office of the State Council, the Shanghai Big Data Center will bring the IPv6 upgrading of the government websites into the supervision from 2019. From July, 2020, report the IPv6 upgrade and transformation of the homepage of each website every month; At the same time, this work will be included in the annual evaluation of government websites to maintain the effectiveness of IPv6 upgrading.

How dare six medium-sized SUVs be called Coupe? Test drive Jietu X70 Coupe

Speaking of Coupe Coupe, I’m sure you’ve got this in mind. The design of the big slipback is very avant-garde. However, although this model brought to you today is called Coupe, it is not quite close to the design of the slipback we imagined, but it has quite excellent face value and rich configuration. It is the X70 Coupe newly launched by Jietu, with a top price of only 130,000 yuan and a personalized package blessing. It looks quite sensational and dynamic.How does it perform in driving? Don’t worry! We’ll try to show you!

Chery's personality medium-sized SUV is only 130,000 test drive Jietu X70 Coupe- Figure 1

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 2

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 3

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 4

Six-seat medium-sized SUVs also dare to ask Coupe to test drive Jetway X70 Coupe- Figure 1

As usual, let’s take a look at the power data first.JietuX70 CoupeIt is equipped with a 1.6L turbocharged engine with a maximum power of 145kW and a peak torque of 290 N m. In terms of transmission system, it is equipped with a 7-speed dual-clutch gearbox, and the chassis part adopts a front McPherson independent suspension and a rear multi-link independent suspension.

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 5

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 6

In the economic mode, the power output is linear, the adjustment of the accelerator pedal is lazy at the moment, and the initial power output is relatively gentle. This mode is still suitable for stop-and-go Buddhist driving in the city, and relaxing the mentality can bring a relaxed and comfortable driving experience.

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 7

When switching to the sport mode, the response of the accelerator pedal and gearbox becomes positive. Relying on the good power reserve, the overall power output is satisfactory, and it can even provide a certain sense of pushing back when accelerating halfway. Although the power reserve is far from abundant, it is absolutely sufficient. Positive response can give drivers enough confidence to complete acceleration and overtaking in daily driving.

Chery's personality medium-sized SUV is only 130,000 test drive Jietu X70 Coupe- Figure 1

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 2

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 3

The 7-speed dual-clutch gearbox performs fairly well during driving, and the response of the gearbox plays a vital role in the acceleration performance of the vehicle. When shifting gears, it can ensure the power to be coherent and smooth. Even if the throttle and brake are frequently operated in congested road conditions, the gearbox can intelligently maintain the appropriate gear and suddenly step on the throttle to accelerate rapidly.Although the response is half a beat slow, butIt can also shift down two gears to ensure power transmission.

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 4

Suspension filters most bumps and undulations on the road surface, and can also pull the car body in time after throwing and jumping to avoid unnecessary shaking, and it is also excellent for handling finely bumpy roads. The overall adjustment is quite stable, even as a tall SUV, the suppression of roll is excellent, which greatly enhances driving confidence.

Chery's medium-sized SUV has only 130,000 test drives. Jietu X70 Coupe- Figure 5

Previously, my colleagues have been right.Jietu X70 Coupe has made a real shot analysis. Why is it called a personalized SUV? You can go to the article above to find the answer.

Chery's personality medium-sized SUV is only 130,000 test drive Jietu X70 Coupe- Figure 1

Going back to the original question of the article, first of all, the power combination of 1.6T+7DCT installed on Jetway X70 Coupe is not full of power, butIt is completely enough for home use, and the mature and steady chassis adjustment and steering settings also bring a very comfortable driving texture. Combined with its landing price of only 130,000 yuan, it is a shortcut.X70 Coupe has extremely practical and durable quality, and it is considered as a leader in its class.

Geely launched the "year-end replacement car purchase season" promotion with a maximum subsidy of 47,000 yuan.

Yichexun A few days ago, Geely launched the "year-end replacement car purchase season" promotion, and the subsidy will be as high as 47,000 from now until December 31.

Specifically, for the model, the carnival price of Xingrui Oriental Yao good car starts from 99,700 yuan, and the subsidy for trade-in is as high as 35,000 yuan; The carnival price of Xingrui good car starts from 99,700 yuan, and the subsidy for trade-in is as high as 37,000 yuan; The carnival price of Zhiqing good car starts from 119,700 yuan, and the subsidy for trade-in is as high as 37,000 yuan.

Series models, the carnival price of Xingyue L Dongfang Yao good car starts from 157,700 yuan, and the subsidy for trade-in is as high as 42,000 yuan; The carnival price of Xingyue L good car starts from 132,700 yuan, and the subsidy for trade-in is as high as 45,000 yuan; The carnival price of Xingyue L Zhiqing good car starts from 152,700 yuan, and the subsidy for trade-in is as high as 37,000 yuan.

Bo models, the carnival price of new cars starts from 103,700 yuan, and the subsidy for trade-in is as high as 39,000 yuan; The carnival price of new cars starts from 87,800 yuan, and the subsidy for trade-in is as high as 30,000 yuan.

Luxury models, the carnival price of the fourth generation of good cars starts from 50,900 yuan, and the subsidy for trade-in is as high as 34,000 yuan; The carnival price of good cars starts from 89,800 yuan, and the subsidy for trade-in is as high as 47,000 yuan; The exclusive car carnival price starts from 143,900 yuan, and the trade-in subsidy is as high as 43,000 yuan.

The carnival price of the super version of the good car starts from 60,800 yuan, and the subsidy for trade-in is as high as 25,000 yuan; The carnival price of good cars starts from 79,800 yuan, and the subsidy for trade-in is as high as 29,000 yuan; The carnival price of COOL cars starts from 74,800 yuan, and the subsidy for trade-in is as high as 34,000 yuan.

The carnival price of Geely’s good car starts from 89,900 yuan, and the subsidy for trade-in is as high as 29,000 yuan.

Editor in charge: Guan Xuetao

399,800 on sale, MINI has placed "blood capital"!

It is no exaggeration to say that space and comfort are important indicators for consumers to choose a car at present, because most people’s appeal is to take a family to travel. What I want to introduce to you today is. Next, let’s see if its highlights can attract you.

先看下MINI JCW COUNTRYMAN的外观,MINI JCW COUNTRYMAN车头整体看上去较为独特,看起来十分精美。再配合端庄的前车灯,使整车精致度得到了大大的提升。该车配备了LED日间行车灯、,自动开闭,自适应远近光,延时关闭等。来到车侧,该车车身尺寸是4447MM*1843MM*1643MM,该车采用了朴素的线条,车身给人一种十分稳重的感觉,搭配大尺寸厚壁的轮胎,造型抢眼。车尾设计上,MINI JCW COUNTRYMAN车尾线条硬朗,尾灯风格较为棱角分明,造型比较前卫。

来到车内,内饰造型看上去十分犀利,视觉效果非常的不错。该车方向盘非常符合内饰风格,采用了真皮材质,一切显得十分炫酷。看一下中控,该车饰以棱角分明的触控式液晶中控屏,让内饰设计颇具层次感,显得精致。内饰给人感觉都不错,再来看看仪表盘和座椅,仪表盘设计可圈可点,信息读取简便清晰。该车采用了皮/织物混搭座椅,座椅宽大厚实,支撑性和舒适性不错。

MINI JCW COUNTRYMAN匹配湿式双离合(DCT)变速箱,百公里加速时间为5.4s,动力表现不错,满足日常使用完全OK。

MINI JCW COUNTRYMAN后排空间表现中规中矩,腿部空间还算富裕,满足日常家用完全没有问题。同时,该车配备了疲劳提醒、刹车防抱死(ABS)、LED日间行车灯、刹车辅助(EBA/BAS等)、制动力分配(EBD)主驾驶安全气囊、副驾驶位安全气囊、侧安全气帘、前排侧安全气囊等安全配置。

这个级别的车型通常是大多数人的首选,首先价格不贵,其次各项配置都挺齐全,还是非常值得入手的。 这款车你也一定要去看下,绝对会带给你意想不到的惊喜。