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General Office of the State Council about

Opinions on accelerating the development of new foreign trade formats and new models

Guo Ban Fa [2021] No.24

People’s governments of all provinces, autonomous regions and municipalities directly under the Central Government, ministries and commissions and institutions directly under the State Council:

The new format and new mode are the effective force of China’s foreign trade development and an important trend of international trade development. Accelerating the development of new foreign trade formats and new models is conducive to promoting the high-quality development of trade, cultivating new advantages in participating in international economic cooperation and competition, and playing an important role in building a new development pattern for services. In order to thoroughly implement the decision-making arrangements of the CPC Central Committee and the State Council, and promote the healthy, sustainable and innovative development of new foreign trade formats and new models, with the consent of the State Council, we hereby put forward the following opinions:

I. General requirements

(1) Guiding ideology.Guided by Socialism with Chinese characteristics Thought of the Supreme Leader in the New Era, we will fully implement the spirit of the 19th National Congress of the Communist Party of China and the Second, Third, Fourth and Fifth Plenary Sessions of the 19th National Congress, adhere to the general tone of striving for progress while maintaining stability, base ourselves on the new development stage, implement the new development concept, build a new development pattern, deepen the "streamline administration, delegate power, strengthen regulation and improve services" reform in foreign trade with the supply-side structural reform as the main line, and promote institutional innovation, management innovation, service innovation, format innovation and model innovation in foreign trade.

(2) Basic principles.

Insist on encouraging innovation. Give full play to the decisive role of the market in resource allocation, better play the role of the government, and further release the vitality of market players. We will try first, encourage the extensive use of new technologies and tools in the field of foreign trade, promote the transformation and upgrading of traditional formats, refine the division of trade, enhance the level of specialization, promote the integration and innovation of formats, and constantly explore new foreign trade formats and models.

Adhere to tolerance and prudence. Make overall plans for development and safety, and insist on standardization in development and development in standardization. Establish and improve a policy system that adapts to the development of new foreign trade formats and new models. Improve standards and systems in information data, credit system and intellectual property protection. Scientifically and reasonably define the platform responsibility. Strengthen supervision after the event, continuously optimize the business environment and promote fair competition.

Adhere to open cooperation. Coordinate the domestic and international markets and resources, adhere to the strategy of mutual benefit and win-win, and promote the liberalization and facilitation of trade and investment. Strengthen cooperation and linkage among departments, localities, industries and enterprises, and improve the efficiency of government management and service. Actively explore the establishment of international rules to adapt to and lead the development of new foreign trade formats and new models, and promote high-level opening up.

(3) development goals.By 2025, the institutional mechanism and policy system for the development of new foreign trade formats and new models will be more perfect, the business environment will be more optimized, and a number of leading enterprises and industrial clusters with international competitiveness will be formed, and the level of industrial value chain will be further improved, which will further enhance the driving role of foreign trade and national economy. By 2035, the development level of new foreign trade formats and new models will be in the forefront of innovative countries, the laws and regulations system will be more perfect, and the degree of trade liberalization and facilitation will reach the advanced level in the world, providing strong momentum for the high-quality development of trade and strong support for the basic realization of socialist modernization.

Second, actively support the use of new technologies and tools to empower foreign trade development.

(four) to promote the application of digital intelligence technology.Use digital technology and digital tools to promote the optimization and upgrading of all links in the whole process of foreign trade. Give play to the "long tail effect", integrate fragmented orders and broaden the channels for obtaining orders. Vigorously develop digital exhibitions, social e-commerce, product crowdfunding, big data marketing, etc., and establish a marketing system with online and offline integration and domestic and overseas linkage. Integrate data of all links in foreign trade supply chain, and strengthen resource docking and information sharing. By 2025, the level of digitalization and intelligence of foreign trade enterprises will be significantly improved.(The Ministry of Commerce takes the lead, and all relevant units are responsible according to the division of responsibilities)

(5) Improve cross-border e-commerce development support policies.Apply the supervision mode of cross-border e-commerce enterprise-to-enterprise (B2B) direct export and cross-border e-commerce export overseas warehouse throughout the country, and improve the supporting policies. Facilitate cross-border e-commerce import and export return management. Optimize the list of cross-border e-commerce retail imports. Steadily carry out the pilot work of cross-border e-commerce retail import drugs. Guide enterprises to make good use of cross-border e-commerce retail export value-added tax, consumption tax exemption policies and income tax verification and collection methods. Study and formulate guidelines for intellectual property protection of cross-border e-commerce and guide cross-border e-commerce platforms to prevent intellectual property risks. By 2025, the cross-border e-commerce policy system will be further improved, the development environment will be further optimized, and the development level will be further improved.(The Ministry of Commerce takes the lead, and the Ministry of Finance, the General Administration of Customs, the State Administration of Taxation, the State Administration of Foreign Exchange, National Medical Products Administration and China National Intellectual Property Administration are responsible according to the division of responsibilities)

(six) solidly promote the construction of cross-border electronic commerce comprehensive experimental zone.Expand the pilot scope of cross-border electronic commerce Comprehensive Experimental Zone (hereinafter referred to as the Comprehensive Experimental Zone). Actively carry out pilot projects, further improve the "two platforms" of cross-border e-commerce online integrated services and offline industrial parks, and the "six systems" of supervision and services such as information sharing, financial services, intelligent logistics, e-commerce integrity, statistical monitoring and risk prevention and control, and explore more good experiences and good practices. Encourage cross-border e-commerce platforms, operators, supporting service providers and other entities to become bigger and stronger, and accelerate the cultivation of independent brands. Establish an assessment and withdrawal mechanism for the comprehensive test area, and organize the assessment and evaluation in 2021. By 2025, the construction of the comprehensive test area has achieved remarkable results, and a number of cross-border e-commerce offline industrial parks with concentrated elements, diverse subjects and professional services have been built, forming a unique development pattern and becoming an innovative cluster leading the development of cross-border e-commerce.(The Ministry of Commerce takes the lead, and the Central Network Information Office, the National Development and Reform Commission, the Ministry of Industry and Information Technology, the Ministry of Finance, the Ministry of Transport, the People’s Bank of China, the General Administration of Customs, the State Administration of Taxation, the General Administration of Market Supervision, China Banking and Insurance Regulatory Commission, the State Post Bureau and the State Administration of Foreign Exchange are responsible for the division of responsibilities.)

(seven) to cultivate a number of outstanding overseas warehouse enterprises.Encourage traditional foreign trade enterprises, cross-border e-commerce and logistics enterprises to participate in the construction of overseas warehouses, improve the digitalization and intelligence level of overseas warehouses, promote small and medium-sized enterprises to borrow ships to go to sea, and drive domestic brands and dual-innovation products to expand the international market space. Support the comprehensive use of investment and financing methods such as BOT and structured financing to invest in overseas warehouse construction. Give full play to the role of foreign embassies and consulates and business organizations, provide early guidance services for overseas warehouse enterprises, and help resolve disputes. By 2025, we will strive to cultivate about 100 outstanding overseas warehouse enterprises with outstanding performance in information construction, intelligent development, diversified services and localized operation.(The Ministry of Commerce takes the lead, and the Ministry of Foreign Affairs, the National Development and Reform Commission and China Banking and Insurance Regulatory Commission are responsible according to the division of responsibilities)

(8) Improve the overseas warehouse network covering the whole world.Support enterprises to speed up the layout of overseas warehouses in key markets, improve the global service network, and establish transportation and sales channels for China brands. Encourage overseas warehouse enterprises to connect with online comprehensive service platforms in the comprehensive test area and domestic and foreign e-commerce platforms to match supply and demand information. Optimize policies and measures such as express transportation, support overseas warehouse enterprises to establish and improve logistics systems, extend services to the upstream and downstream of the supply chain, and explore the construction of overseas logistics smart platforms. Promote the construction of overseas warehouse standards. By 2025, relying on overseas warehouses to establish a new foreign trade logistics network with global coverage and coordinated development, and launch a number of internationally influential national and industry standards.(The Ministry of Commerce takes the lead, and the National Development and Reform Commission, the Ministry of Transport, the General Administration of Market Supervision and the State Post Bureau are responsible according to the division of responsibilities.)

Third, continue to promote the transformation and upgrading of traditional foreign trade

(nine) to enhance the digital level of traditional foreign trade.Support traditional foreign trade enterprises to use advanced technologies such as cloud computing, artificial intelligence and virtual reality, strengthen research and development design, and carry out intelligent, personalized and customized production. Encourage enterprises to explore the construction of big data laboratories for new foreign trade formats. Guide the use of digital means to enhance the value of traditional brands. Encourage the construction of incubation institutions and innovation centers, and support the entrepreneurial innovation of small and medium-sized enterprises. By 2025, a foreign trade industrial chain supply chain system driven by new formats, supported by big data, networked sharing and intelligent cooperation will be formed.(The Ministry of Commerce takes the lead, and all relevant units are responsible according to the division of responsibilities)

(ten) to optimize the policy framework of market procurement trade mode.Improve the dynamic adjustment mechanism of market procurement trade mode pilot, set up comprehensive evaluation indicators, and give better play to the demonstration and leading role of pilot areas. Support each pilot area to explore and innovate according to local conditions, attract more domestic trade subjects to carry out foreign trade, guide market subjects to improve quality, technology, service and brand, enhance product competitiveness, and amplify the agglomeration and driving effect on surrounding industries. By 2025, we will strive to cultivate about 10 integrated domestic and foreign trade markets with exports exceeding 100 billion yuan and build a number of well-known brands.(The Ministry of Commerce takes the lead, and the National Development and Reform Commission, the Ministry of Finance, the General Administration of Customs, the State Administration of Taxation, the General Administration of Market Supervision and the State Administration of Foreign Exchange are responsible according to the division of responsibilities.)

(eleven) to improve the level of market procurement and trade facilitation.Further optimize the comprehensive management system of market procurement and trade, and realize traceability, risk control and accountability. We will continue to implement pilot policies such as simplified customs declaration and exemption of value-added tax for goods exported by market procurement trade, and optimize the customs clearance process. Expand the pilot scope of market procurement trade prepackaged foods export. Guide banks to provide more convenient financial services for market procurement trade income filed in the comprehensive management system of market procurement trade and traceable to the authenticity of transactions.(The Ministry of Commerce takes the lead, and the National Development and Reform Commission, the Ministry of Finance, the People’s Bank of China, the General Administration of Customs, the State Administration of Taxation, the General Administration of Market Supervision, and the State Administration of Foreign Exchange are responsible according to the division of responsibilities.)

Four, further promote the development of foreign trade services to professional segmentation.

(twelve) to further support the healthy development of foreign trade comprehensive service enterprises.Implement the centralized tax refund filing work and improve work efficiency. For the production enterprises that have filed the tax refund on behalf of the agency but have not yet made the on-site inspection of the first tax refund (exemption), the efficiency of the on-site inspection will be further improved after receiving the declaration information of the first tax refund business entrusted by the agency. Guide foreign trade comprehensive service enterprises (hereinafter referred to as comprehensive service enterprises) to standardize internal risk management and improve the risk management and control level of centralized agency tax refund. Further implement and improve the "double penalty" mechanism of the customs. Under the condition that the comprehensive service enterprise strictly fulfills its reasonable review obligation and there is no intentional or gross negligence, the comprehensive service enterprise and its customers will bear corresponding responsibilities according to the circumstances. By 2025, the policy environment to adapt to the development of comprehensive service enterprises will be further optimized.(The Ministry of Commerce takes the lead, and the General Administration of Customs and the State Administration of Taxation are responsible according to the division of responsibilities.)

(thirteen) to improve the development level of bonded maintenance business.Further support enterprises in the comprehensive bonded area to carry out maintenance business, dynamically adjust the catalogue of maintenance products, and study the inclusion of medical devices and other products in the catalogue. Support enterprises in the Pilot Free Trade Zone to carry out bonded maintenance business with "two ends in the outside" according to the catalogue of maintenance products in the comprehensive bonded zone. The provincial people’s government where the Pilot Free Trade Zone is located will comprehensively evaluate the maintenance projects and independently support them, and assume the main responsibility for the supervision and other matters of the supported projects. Explore and support qualified enterprises outside the comprehensive bonded zone to carry out bonded maintenance of self-produced export products with high technology content, high added value and meeting environmental protection requirements, promote it steadily by pilot, strengthen evaluation, and study and formulate management measures and maintenance product lists. By 2025, the policy system of bonded maintenance business will be gradually improved.(The Ministry of Commerce takes the lead, and the Ministry of Finance, the Ministry of Ecology and Environment, the General Administration of Customs and the State Administration of Taxation are responsible according to the division of responsibilities.)

(14) Steadily promote the development of offshore trade.Encourage banks to explore and optimize business authenticity audit methods, improve audit efficiency based on customer credit classification and business model according to the principle of exhibition industry, provide high-quality financial services for enterprises to carry out true and compliant offshore trade business, and improve the level of trade settlement facilitation. Further strengthen the innovation of offshore trade business in the Pilot Free Trade Zone, and support qualified cities and regions with strong competitiveness and management capabilities to develop offshore trade.(The Ministry of Commerce, the People’s Bank of China and the State Administration of Foreign Exchange are responsible for the division of responsibilities)

(fifteen) support the development of foreign trade segmentation service platform.Support sharing and innovation in foreign trade segments such as marketing, payment, delivery, logistics and quality control. Encourage foreign trade segmentation service platforms to deepen vertical markets in various regions and industries and take the road of "specialization and innovation". Encourage foreign trade enterprises to build their own independent stations, and support professional station building platforms to optimize and improve service capabilities. Explore the application of blockchain technology in the field of trade segmentation. By 2025, a number of foreign trade segmentation service platform enterprises with strong international influence will be formed.(The Ministry of Commerce takes the lead, and all relevant units are responsible according to the division of responsibilities)

V. Optimizing the policy guarantee system

(sixteen) innovative supervision methods.According to the needs of the development of foreign trade formats, we should study and improve relevant laws and regulations in a timely manner and scientifically set up an "observation period" and a "transition period". Introduce the "sandbox supervision" mode to provide a safe space for business innovation. Promote data docking among departments such as commerce, customs, taxation, market supervision and postal services, and strengthen supervision over tax evasion, counterfeiting and false transactions while optimizing services. Improve the statistical system of new foreign trade formats and new models.(The Ministry of Commerce takes the lead, and the General Administration of Customs, the State Administration of Taxation, the General Administration of Market Supervision, the National Bureau of Statistics and the State Post Bureau are responsible according to the division of responsibilities.)

(seventeen) the implementation of fiscal and taxation policies.Give full play to the role of special funds for foreign trade and economic development and guiding funds for the innovation and development of service trade, and guide social capital to support the development of new foreign trade formats and new models by means of funds. Actively explore and implement tax collection and service measures to promote the development of new foreign trade formats and new models, and optimize the relevant tax environment. Enterprises that support new foreign trade formats and new models apply paperless methods to declare tax rebates. Enterprises with new foreign trade formats and new modes that have been identified as high-tech enterprises can enjoy preferential income tax policies for high-tech enterprises according to regulations.(The Ministry of Finance, the Ministry of Commerce and the State Administration of Taxation are responsible for the division of responsibilities)

(eighteen) increase financial support.Deepen the cooperation between government, banks and enterprises, actively promote the "credit-easy loan" model, encourage financial institutions, non-bank payment institutions, credit reporting institutions and foreign trade service platforms to strengthen cooperation, and provide convenient financial services for enterprises with new foreign trade formats and new models with real trading background. Encourage qualified enterprises with new foreign trade formats and new modes to raise funds through listing and issuing bonds. Accelerate the construction of a trade and financial blockchain platform. We will increase the support of export credit insurance for new foreign trade formats and new models such as overseas warehouses, and actively play the role of risk protection and financing promotion.(The National Development and Reform Commission, the Ministry of Finance, the Ministry of Commerce, the People’s Bank of China, China Banking and Insurance Regulatory Commission, the CSRC, the State Administration of Foreign Exchange, the Export-Import Bank and China Export Credit Insurance Corporation are responsible for the division of responsibilities.)

(nineteen) convenient trade payment and settlement management.We will deepen the pilot project of facilitating foreign exchange receipts and payments, and support more qualified banks and payment institutions to provide settlement services for enterprises with new foreign trade formats and new models in accordance with laws and regulations. Encourage research and development of safe and convenient cross-border payment products, and support non-bank payment institutions to "go global". Encourage foreign-funded institutions to participate in the development and competition of the payment service market in China.(The People’s Bank of China and the State Administration of Foreign Exchange are responsible for the division of responsibilities)

Sixth, create a good environment

(twenty) to maintain a good foreign trade order.Strengthen anti-monopoly and anti-unfair competition regulations, focus on preventing and stopping monopoly and unfair competition in new foreign trade formats, protect fair competition and prevent disorderly expansion of capital. Explore the establishment of a credit evaluation system for enterprises with new foreign trade formats and new models, and encourage the establishment of an important product traceability system. Support the formulation of national, industrial and local standards in the field of new foreign trade formats, and encourage industry associations to formulate relevant group standards.(The Ministry of Commerce, the National Development and Reform Commission, the General Administration of Customs and the General Administration of Market Supervision are responsible for the division of responsibilities)

(twenty-one) to promote the construction of new foreign trade infrastructure.Support the construction of online comprehensive service platform and digital public service platform in the field of foreign trade. Encourage telecom enterprises to provide dedicated channels for Internet data for foreign trade enterprises to carry out digital marketing. Improve the layout of the international mail exchange bureau (exchange station) and the international express processing center. Open a special train between China and Europe to meet the needs of new foreign trade formats and new modes to develop transportation.(The Ministry of Commerce, the National Development and Reform Commission, the Ministry of Industry and Information Technology, the State Post Bureau and China National Railway Group Co., Ltd. are responsible for the division of responsibilities)

(twenty-two) to strengthen the construction of industry organizations and professional personnel training.Promote the establishment of relevant industry organizations in the field of new foreign trade formats according to law, and introduce industry service norms and self-discipline conventions. Encourage ordinary colleges and vocational colleges to set up related majors. Guide ordinary universities, vocational colleges and enterprises to cooperate, and cultivate management talents and high-quality technical and technical talents that meet the needs of the development of new foreign trade formats and new models.(The Ministry of Commerce, the Ministry of Education and the Ministry of Civil Affairs are responsible for the division of responsibilities)

(23) Deepen international exchanges and cooperation.Actively participate in multilateral and bilateral negotiations such as the WTO and the Universal Postal Union, and promote the formation of international standards on electronic signatures, electronic contracts and electronic documents. Strengthen international cooperation in the fields of intellectual property protection and transnational logistics, and participate in the formulation of international rules and standards for new foreign trade formats and new models. Strengthen intergovernmental cooperation with relevant countries in related fields and promote two-way opening up. Vigorously develop silk road e-commerce and strengthen the "Belt and Road" economic and trade cooperation. Promote the connection between China’s new foreign trade format and new mode and foreign circulation industry. Encourage all localities, pilot units and enterprises to carry out international exchanges and cooperation.(The Ministry of Commerce takes the lead, and all local people’s governments and relevant units are responsible according to the division of responsibilities.)

Seven, do a good job in organizing the implementation

(twenty-four) to strengthen organizational leadership.Give full play to the role of the State Council in promoting the inter-ministerial joint conference system of high-quality trade development, strengthen departmental linkage and coordination between the central and local governments, and coordinate and solve major problems. All regions and relevant departments should implement it in accordance with the division of responsibilities, cooperate closely, introduce relevant measures in a timely manner, and continue to explore and practice boldly. The Ministry of Commerce should strengthen work guidance with relevant departments to ensure that all measures are effective.(The Ministry of Commerce takes the lead, and all local people’s governments and relevant units are responsible according to the division of responsibilities.)

(twenty-five) do a good job in publicity and promotion.Constantly sum up and promote good experiences and good practices. Strengthen the guidance of public opinion and announce the development effect of new foreign trade formats and new models. Actively create a good atmosphere of encouraging innovation, full of vitality, fair competition, standardization and order, and promote the healthy, sustainable and innovative development of new foreign trade formats and new models.(The Ministry of Commerce takes the lead, and all local people’s governments and relevant units are responsible according to the division of responsibilities.)

the General Office of the State Council

July 2, 2021

(This piece is publicly released)

Xinhua News Agency, Beijing, June 8 (Reporter Xie Xiyao, Zou Duowei) Li Xinggan, director of the Foreign Trade Department of the Ministry of Commerce, said on the 8 th that since the beginning of this year, with the gradual recovery of production in neighboring countries, some foreign trade orders that returned to China last year have flowed out again. Overall, the scale of these orders outflow is controllable and the impact is limited.

This is what Li Xinggan said in response to a reporter’s question about the order outflow and industrial relocation of some domestic industries at the routine briefing on the State Council policy held that day. He said that the relocation of some industries conforms to the economic law, and China has been ranked as the world’s largest exporter of goods for 13 consecutive years. With the continuous upgrading of domestic industries, the factor structure is changing, and some enterprises take the initiative to make global layout and transfer some of their manufacturing links abroad, which is a normal phenomenon of division of labor and cooperation in trade and investment.

Li Xinggan emphasized that China’s position in the global industrial chain supply chain pattern is still consolidated. China has a complete industrial system, obvious advantages in infrastructure, industrial supporting capacity and professional talents, and the business environment is constantly optimized, and the attractiveness of the super-large-scale market is constantly increasing. In the first four months of this year, the actual use of foreign capital in China increased by 20.5% year-on-year, equivalent to 26.1% year-on-year.

Talking about how to fully help foreign trade enterprises to guarantee orders, expand markets and stabilize industries, Li Xinggan said that it is necessary to promote effective policies and measures, fully help foreign trade enterprises to resume work and reach production, and comprehensively restore and continuously enhance the comprehensive competitiveness of foreign trade enterprises in China; Strengthen the service guarantee of enterprises and make every effort to help solve the difficulties and problems encountered by foreign trade enterprises in trade facilitation, logistics and transportation, and obtaining orders; Guide the optimal layout of production capacity, guide the gradient transfer of industries to the central and western regions and northeast regions, and guide qualified enterprises to carry out global layout in an orderly manner.

Li Xinggan emphasized that we should firmly promote the high-level opening up, implement the Regional Comprehensive Economic Partnership Agreement (RCEP) with high quality, continue to promote the strategy of upgrading the Free Trade Zone, continue to promote the accession to the Comprehensive and Progressive Trans-Pacific Partnership Agreement (CPTPP) and the Digital Economy Partnership Agreement (DEPA), and standardize the international trade rules, so that China will always become a hot spot for foreign investment.

Original Time School Research Institute Time School is included in the topic # 56 anti-aging substances.

editorial comment/note

Curcumin, which is a’ youth medicine’ and a delicious food, has always had its own place in the anti-aging circle, but it is safe and has no toxic and side effects, but it has not yet been among the top anti-aging products. If you want to listen carefully to the reasons, let’s start with the story of curcumin. ……

Last time, we talked about that a large number of cellular, molecular and clinical studies have proved that curcumin has multiple effects such as anti-inflammatory, anti-oxidation, anti-cancer and anti-microbial (click Review:), but why hasn’t curcumin been licensed and can’t it play a higher role in disease treatment?

Look at people by their character, and look at chemicals by their physical and chemical properties. First of all, we should grasp two characteristics of curcumin: low solubility and unstable chemical properties. Remember these two clues, and the following stories are based on them ~

Low solubility

There is a large hydrophobic region in the molecular structure of curcumin, which determines its basic characteristics of low water solubility. However, there are three hydroxyl groups in its molecular structure, so when the alkalinity is high enough, the charged hydrogen ions will be dissociated, and the curcumin molecule will also be negatively charged, and the water solubility will increase [1]. To put it simply, it is insoluble in water, and the more alkaline it is, the more soluble it is.

instability

Curcumin is a difficult master, and it will change when the environment is a little unsatisfactory. As mentioned above, the greater the alkalinity of the solution, the more curcumin is dissolved, which provides great convenience for the hydrolysis reaction; In addition, curcumin is also easy to occur in the presence of light; What’s more, curcumin may spontaneously oxidize when there is no stimulus! Although so many degradation products have more or less anti-inflammatory and anti-cancer effects, the "periphery" is not as powerful as the "main body" [2].

Then we need to know what curcumin has experienced from eating to discharging, as shown in the following figure [3]:

There are three paths for curcumin to enter digestive tract.

1. In the original form, excreted by feces, jump to the ending 1.

2. After being metabolized by enzymes in digestive tract, it is excreted by feces in the form of metabolites, and jumps to the end 1.

3. Escaped from the clutches of digestive tract enzymes, successfully approached intestinal epithelial cells and entered path B.

There are two ways for curcumin to get close to intestinal epithelial cells.

1. Thrown back to the intestine by the ruthless porters of intestinal epithelial cells, and returned to the path A.

2. Being sent into the blood circulation by the friendly porters of intestinal epithelial cells and entering the path C.

There are two ways for curcumin to reach the liver after it enters the blood circulation.

1. It is metabolized by enzymes in the liver and enters the systemic blood circulation in the form of metabolites, and enters the path D.

2. Escaped from the clutches of liver enzymes, and entered the systemic blood circulation in its original form, and also entered the path D.

After curcumin or its metabolites enter the systemic blood circulation, there are two paths.

1. Enter the kidney with blood, then enter the urine, and pass out of the body with urine, and jump to the end 2.

2. With the distribution of blood to various organs and tissues of the whole body (such as brain, lung, heart, muscle, etc.), it plays an anti-inflammatory, anti-oxidation and anti-cancer role, and jumps to the ending 3.

Obviously, we have high hopes for the ending 3, but how many "difficulties and dangers" does curcumin have to go through to get on this right path? And don’t forget curcumin’s bad temper (low solubility and low stability), so it is even more difficult for it to "survive" success. Therefore, scientists have developed a lot of equipment for curcumin in order to help it succeed.

The role played by these equipments can be summarized as two aspects:

On the one hand, it improves its basic performance (increasing solubility and stability), and on the other hand, it specifically resists "enemy" forces (such as antagonistic cell efflux transporters). The following table is a summary of various methods and principles to improve the absorption and utilization rate of curcumin [3]:

Method type

give an example

principle

Control environmental conditions

Use organic solvents

Increase solubility

Adjust pH

Increase stability

Combined adjuvant

Piperine, catechin, etc.

Inhibition of efflux transporter

Antioxidants such as ascorbic acid and gallic acid.

Increase stability and reduce oxidative degradation.

Packaging technology/carrier technology

Micellar, microemulsion, hydrophobic biopolymer particles, liposomes, etc.

Increase dispersibility in water; Isolate water phase to increase stability; Increase the affinity with tissues and cells

In the research of pushing curcumin into clinical application, the obstacles encountered are not only the above physical and chemical characteristics and biological characteristics of curcumin, but also the research itself:

First of all, curcumin used in various studies is actually different. Most crude extracts made from turmeric and even some refined "curcumin" raw materials contain three main compounds: curcumin, demethoxycurcumin and bis-demethoxycurcumin, and a few secondary metabolites.

The ratio of curcumin compounds in various "curcumin preparations" is different, and the types of curcumin compounds used in experimental research are also different (pure curcumin is often used in in vitro research and more is artificially synthesized, while the mixture of curcumin compounds is often used in in in vivo research and clinical trials), but curcumin is often used as the active ingredient to evaluate the efficacy. In addition, the dosage form and dosage of curcumin used in each experiment are also different. Therefore, it is difficult to compare the effects of curcumin between different studies, and it is difficult to get a consistent conclusion [5].

///

On the other hand, curcumin is a pan-screening interfering compound, which makes it difficult for researchers to judge whether curcumin plays a role in a certain target.

The so-called pan-screening interfering compounds mean that they do not act on the target target but present a sharply confusing false positive result.

Real drugs can precisely act on specific protein binding sites, thus inhibiting or activating the function of protein. The "false positive compounds" are disguised as drug combinations, and smoke bombs are released in various screening studies. Moreover, curcumin does have a wide range of biological activities, just like an all-round sports fan who can win an excellent participation award in various competitions. Therefore, it is not a simple matter to judge whether curcumin has played a valuable role in some way and can be detected correctly [5].

With this explanation, it seems that curcumin is still far from being used as medicine, but there is no need to worry. The above problems are what scientists are trying to solve.

Last time, I made it clear that clinical studies show that taking curcumin up to 12g per day has no side effects, and the FDA also lists curcumin as a recognized safe food additive. We often eat curry, which is healthy and delicious. Isn’t it delicious? As a dietary supplement, curcumin products can also be eaten.

The following summarizes some kinds of turmeric derivatives in life and their uses [6]:

kind

character

use

Curcuma rhizome (intact)

Orange-brown rhizome (dry)

medicinal

Turmeric powder

Red and yellow powder, made by grinding dried rhizome.

Medicine, spices, dyes, dietary supplements

Turmeric resin

Brown viscous liquid, extracted from roots or leaves.

Medicinal, food colorants, dietary supplements

Ginger butter

Brown oil, extracted from roots or leaves.

Medicine, spices, dietary supplements

Curcumin

Orange-red crystalline powder, extracted and purified from turmeric powder.

Medicinal and dietary supplements

Once again, the content of this article is not used to persuade people to quit. We are just adhering to the consistent style, putting facts and being reasonable! Curry tastes good, so can curcumin ~

references

[1] Bernabé-Pineda M., Ram?rez-Silva M.a.T., Romero-Romo M., González-Vergara E., Rojas-Hernández A. Determination of acidity constants of curcumin in aqueous solution and apparent rate constant of its decomposition. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 2004; 60:1091–1097. doi: 10.1016/S1386-1425(03)00342-1.

[2] Priyadarsini KI. The chemistry of curcumin: from extraction to therapeutic agent. Molecules. 2014; 19(12):20091-20112. Published 2014 Dec 1. doi:10.3390/molecules191220091

[3] Zheng B, McClements DJ. Formulation of More Efficacious Curcumin Delivery Systems Using Colloid Science: Enhanced Solubility, Stability, and Bioavailability. Molecules. 2020; 25(12):2791. Published 2020 Jun 17. doi:10.3390/molecules25122791

[4] Xie Tao, Du Guanhua. The pain of Qualcomm’s quantitative screening —— Pan-active screening interfering compounds [J]. Journal of Pharmacy, 2015(08):925-930.

[5] Nelson KM, Dahlin JL, Bisson J, Graham J, Pauli GF, Walters MA. The Essential Medicinal Chemistry of Curcumin. J Med Chem. 2017; 60(5):1620-1637. doi:10.1021/acs.jmedchem.6b00975

[6] Li S., Yuan W., Deng G., Wang P., Yang P., Aggarwal B. B. Chemical composition and product quality control of turmeric (Curcuma longa L.) Pharmaceutical Crops. 2011; 2(1)

If you have any doubts, ideas, or problems in the field of anti-aging, welcome to discuss them in the comment area!

Original title: "Anti-cancer is short, life expectancy is insufficient, and the anti-aging" new star "curcumin is a complete scam? ! 》

Read the original text

　　Judicial trial data is the most intuitive reflection of the trial work, and the Supreme Court emphasized in advance that courts at all levels should "resolutely put an end to not accepting cases at the end of the year".

　　On October 17th, the Supreme People’s Court held a consultation on data analysis and judgment of judicial trials in the first three quarters of 2023. Zhang Jun, president of the Supreme Court, said that the quality, efficiency and effectiveness of trials in the first three quarters of the country have steadily increased, and it is necessary to strictly implement the requirements of the settlement rate within the trial limit, and no longer use the annual settlement ratio and settlement rate indicators, and resolutely put an end to not accepting cases at the end of the year.

　　At the chamber of commerce, the leaders of the Supreme Court and the heads of various business chambers spoke line by line in combination with detailed data reports, problems reflected in case trials and problems found in field research, and put forward opinions and suggestions on strengthening and improving the work.

　　"Since the two sessions this year, we have conducted three data meetings, and the analysis and judgment have become more and more in-depth and accurate, and a fixed mechanism has been formed. In view of the problems found in the data consultation, each business office deeply analyzes the reasons and studies the improvement measures in combination with the actual work, and has done a lot of extra-case ‘ Grasp the front end and cure the disease before it happens ’ The work of grasping the quality and efficiency of trials has achieved remarkable results. " Zhang Jun pointed out that it is necessary to give full play to the role of data consultation, and promote the modernization of judicial work with scientific research and judgment of judicial trial data.

　　Combined with the problems reflected in the data and work measures, Zhang Jun put forward three requirements:

　　First, the Supreme Law should grasp the top priority of judicial trial, pay close attention to studying, improving and perfecting work measures in view of the fact that its own trial execution is not in place, and ensure the successful completion of the trial task throughout the year. For the problem of "debt owed" in the trial work of local courts reflected by the data, it is necessary to urge and guide to seize the time to fill in the shortcomings, while ensuring high quality and efficiency, and preventing "radish from washing the mud".

　　Second, make full use of the results of the consultation, and seriously sum up and popularize the experience of the courts that rank in the top five in terms of data indicators, especially those whose work has improved significantly since this year. For the court whose work is obviously lagging behind, it is necessary to earnestly supervise and guide, and conduct pressure at all levels. The leaders in charge of the hospital and the main responsible comrades of the business department should lead a team to conduct on-the-spot investigation, find out the root cause of the problem and clarify the improvement measures. It is necessary to strictly implement the requirements of the settlement rate within the trial limit, and no longer use the annual settlement ratio and settlement rate indicators. Through scientific trial management, we will resolutely put an end to not accepting cases at the end of the year. Take the initiative to accept the supervision from all walks of life, and verify one case and one case in informed criticism for violating scientific management and leading some grass-roots courts not to accept cases at the end of the year. For cases that may occur at the end of the year, such as arrears of wages for migrant workers, we should take the initiative to judge in advance and promote the settlement as soon as possible.

　　Third, all business courtrooms should enhance their awareness of active justice, carefully study the deep-seated reasons for the increase of a case in each line, take the initiative to communicate with relevant departments and relevant courts, and do the source treatment with the concept of win-win and win-win. On the basis of giving full play to the role of "bringing in" mediation organizations, we should devote more energy to the guidance of "going out", and constantly improve the ability of people’s mediators and industry mediation organizations to resolve disputes through case guidance, business training, and attending court trials. It is necessary to give full play to the role of "answering the law" and improve the ability of judges to understand and apply the law. It is necessary to speed up the construction of the case database of the people’s courts, unify the judgment standards through typical cases, and promote the settlement of similar cases.

　　Since 1976, he began to study high critical temperature superconductors, and his name has always been closely related to superconductivity for half a century.

　　As one of the pioneers who started the research of high-temperature superconductivity in China, he first proposed to explore high-temperature superconductors in China, and first proposed to set up a national superconducting laboratory … … It has made indelible contributions to China’s superconducting development from starting, catching up and being among the forefront of the world when it is 50 years behind.

　　In the history of superconductivity research for more than a hundred years, there have been two major breakthroughs in high-temperature superconductivity. He and his collaborators have made important achievements, namely, independently discovering high-temperature superconductors in liquid nitrogen temperature region and discovering a series of iron-based high-temperature superconductors above 50K and creating a record of 55 K.

　　Today, science and technology have a profound impact on the country’s future and destiny. In the field of high-temperature superconductivity, he and his team are constantly attracting groups of young people and pushing China’s high-temperature superconductivity research to the forefront of the world.

　　He said, "The core science and technology can only be done by ourselves. It is necessary to combine personal interests with the destiny of the country, cooperate in tackling key problems, and serve the country. "

　　He said, "I would like to be a paving stone and let young friends make great achievements."

　　He is the winner of the highest national science and technology award in China in 2016, academician of China Academy of Sciences and physicist Zhao Zhongxian.

　　Sidenote 1: When an old superconducting expert meets an old director of the compilation bureau.

　　There are four old people among the guests who participated in the recording of "Example" this time. Apart from the special guest Mr. Niu Benlao and a veteran member of the National Survey Team, Mr. Yu Qiqing, who was the first to take part in the Everest survey in China, he is the former director of the Central Compilation Bureau, Mr. Song Shusheng, and academician Zhao Zhongxian, a superconducting expert.

　　During the filming, Academician Zhao Zhongxian and Mr. Song Shusheng sat together. One of them leaned back thoughtfully, and the other sat upright and had a straight body. I thought that two doyen in different fields would care for each other and sit together as a pair of quiet handsome men, but there was a special dialogue:

　　"I have read Anti-Turin Theory." Academician Zhao said.

　　"This book is good, it expounds the three components of Marxism, and it is also relatively easy to read … …” Mr. Song Lao also turned around and began to communicate seriously.

　　Compared with HTS, a high-cold scientific research topic, the old academician Zhao Zhongxian himself gives people a much more vivid feeling.

　　He is humorous and honest and frank. From time to time, he uses his loud voice to open the "Tucao" mode, which causes people next to him to laugh. He has a wide range of daily hobbies, and he tries skiing and drifting. Literature, photography, cultural relics in museums and good music in China and the West are all his interests. His heart is firm and soft, with the rigor, strictness and seriousness of scientists, and he always thinks about students and the life and future development of young people.

　　Under his "independent" face, there is warmth, hope, swallows whispering, and flowers blooming from tree to tree.

　　Sidenote 2: "Scientific research is like playing mahjong"

　　When the program was recorded, Academician Zhao Zhongxian was asked: "You have done one thing all your life, and it is something that 99% people in the world don’t understand. How did you persist? " The old gentleman’s spit mode was turned on.

　　"I think many people don’t understand the fun of scientific research, saying that scientific research is a bench and asking me why I can persist for decades. If you like playing mahjong, do you think you can’t stick to it? " The old man said.

　　"Scientific research will encounter such difficulties, but just like people playing mahjong, as long as they are interested, they still want to play if they fail, not to mention that we often draw cards, small and big!"

　　In his mind, the "bench" of scientific research is not always cold. Despite many difficulties, in the process of research, the more you do, the more interested you are. Interest is very important. You are addicted and very willing to do it. At the same time, it is also an encouragement to make new progress in our work. Insisting on doing something has a sublimation of understanding on the basis of long-term accumulation.

　　In a speech, he mentioned how he became interested in science: in 1956, the state proposed "marching into science." As an imaginative and energetic middle school student, he participated in extracurricular activities of the school physics group and read popular science magazines, which led him to like science. He said: Many years later, I gradually realized that understanding science is a kind of enjoyment, which can gain new knowledge, arouse curiosity and enhance interest.

　　He was admitted to China University of Science and Technology in 1959. He said that at that time, many students were willing to study science and engineering, which was the call of the state and very fashionable. Popular majors include atomic bombs, semiconductors, etc. "I remember that the cover of the admissions brochure of the University of Science and Technology of China is the rocket. I think it is this that attracted many students, including me, to apply for China University of Science and Technology. It should be said that the call of the country made many people in our generation choose science and technology. "

　　He said that it is the best choice to combine personal interests with livelihood, and he happened to be very lucky.

　　Sidenote 3: I think it is very important to settle down and do things.

　　In the process of chatting with Mr. Niu Ben, when he mentioned some "short and fast" phenomena in the film industry, Mr. Zhao Zhongxian’s tucao mode was opened again:

　　Now there are so many scientific and technical personnel and teams all over the country. I think it takes a person or a team ten years, or twenty years to solve an important scientific problem or a core technical problem. Does that add up?

　　He said, don’t be eager for quick success, set a long-term goal. "Now these young people have a good foundation, because their education is very complete, their equipment is world-class and their funds are sufficient. I think the current conditions are very good, and the key is to settle down and do things. "

　　He believes that "scientific research is a natural and rising process. You have a group of people who have found the right direction and made unremitting efforts in a down-to-earth manner, and will always make discoveries that are beneficial to the progress of human civilization. " As long as all of us can settle down and concentrate on our work, instead of catching up with the "trend" to do things of the same nature, short-term and quick success, our country’s science and technology will develop faster and better.

　　He said, "I have only done one thing in my life, that is, exploring superconductors and conducting research on superconducting mechanisms. If everyone in our society persists in doing one thing, many problems can be solved. "

　　Sidenote 4: "Academician Zhao speaks the scientific research party class very well."

　　During a chat, Academician Zhao Zhongxian chatted, "I have both Chinese and English versions of The Supreme Leader’s Talks on Governing the Country, and some places in the English version are more clear than the Chinese version."

　　Teacher Dong, the assistant, is sitting on the side. "Academician Zhao speaks the scientific research party class very well."

　　On July 19th, at the China Academy of Sciences’ theme activity of "Patriotism and Dedication, Being the Pioneer of the Times", Academician Zhao Zhongxian was invited to give a special party class to the delegates.

　　He talked about the patriotism, dedication, scholarship and self-cultivation of the older generation of scientists, and that after entering China University of Science and Technology, he was inspired by the knowledge and spirit of the older generation, and gradually changed his love for science when he was young into a sense of responsibility and mission in scientific research.

　　He said that the older generation of scientists taught not only knowledge, but also spirit. In his study and practice, he constantly understood the essence of these famous predecessors’ scholarship, and gradually realized that scientific research needs to take root, and long-term persistence and accumulation will be sublimated in understanding, so as to seize opportunities and accumulate wealth.

　　He said that his 40-year persistence benefited from the stable environment, and he grew up under the inspiration of the spirit of the old Red Army and the patriotic dedication of the older generation of scientists. The most comforting thing is "I gave".

　　He hopes that young friends can settle down and concentrate on their work. "One generation does the work of another generation, and several generations of teachers and students cultivate it to realize the rooting of Chinese science." He also believes that they have the ambition and ability to contribute to building a world-class science and technology power and the progress of human civilization.

　　Sidenote 5: Why can you do one thing all your life?

　　"I have faith and am interested in science."

　　During my brief contact with Academician Zhao Zhongxian, the words "faith" and "interest" impressed me the most. These two words have accompanied his life’s choices and supported his scientific research career for decades.

　　In 1956, the state proposed "marching into science". As an imaginative and energetic middle school student, he took part in extracurricular activities of the school physics group, read popular science magazines, and gradually became fond of science.

　　In 1959, he was admitted to China University of Science and Technology, and listened to the lectures and reports of famous teachers and the relationship between science and technology and the fate of the country. He began to feel that he was not only fond of science, but also had a sense of responsibility and mission.

　　In 1972, China Academy of Sciences won more than 20 places to study abroad, and he was selected to go to Cambridge University in England for further study after applying for superconductivity. He enjoys the experimental work of "nine to ten" and is always full of passion. Seeing the gap in contact with international counterparts, he began to move towards the field of high temperature superconductivity.

　　China, who is in a great hurry, returned to China to lead his team to build their own experimental equipment. The conditions were so hard that he beat mice under the covers. He was still optimistic that his relative disadvantage was not so great. "Compared with other scientific research, the exploration of superconducting materials does not need particularly advanced and complicated instruments. I am willing to make full use of the existing conditions to carry out a project."

　　After decades of high-temperature superconducting research, he felt the regret that he was beaten to the top by one step, and he also experienced the joy of seizing the opportunity when the international competition was the fiercest. I have experienced the frenzied scene of the "Rock Music Festival in Physics" which lasted for more than 7 hours, and I have also been under great pressure to be questioned because of the many achievements of raw materials and impurities used in experimental samples. Or sit on the bench day after day, or add honor to your success. Between ups and downs, his interest remains, his faith remains, and his "initial heart" has never changed.

　　For half a century, he has always been interested in and curious about science as a teenager. "Doing scientific research is like playing mahjong," he said. In the research process, despite many difficulties and addiction, the more you do it, the more interested you are and the more willing you are to do it. Just like mahjong clubs and cards, every progress in work is also encouragement. "

　　Faith is more like a flower in his heart when it is chilly in spring. He said that insisting on doing something will lead to the sublimation of understanding on the basis of long-term accumulation. In day-to-day scientific research, he sees the charming charm of superconductivity, firmly believes that there will be a breakthrough in superconductivity, and firmly believes that his research has great scientific significance and application value, and can contribute to this country, nation and human civilization.

　　He said that a country’s scientific and technological strength can’t be bought with money, and it can only be based on itself. It is necessary to combine personal interests with the destiny of the country, tackle the problem with teeth, and serve the country with knowledge.

　　China Meteorological News correspondent Liu Shouyu reporter Deng Minjia

　　In the early morning of July 7, there was a rainstorm in Fuliang County, Jingdezhen City, Jiangxi Province. As of 20: 00 on the 7th, there was heavy rain in the county, and the precipitation in the upper reaches of Fuliang Town passed through Gongqiao Town, Jiangcun Township and other places exceeded 250 mm, and the water level of Changjiang River soared.

　　Will such heavy rainfall affect the safety of people in low-lying areas? Do you want to transfer people? The county government and township leaders are worried.

　　At 14: 56 on the 7th, the meteorological bureau of Fuliang County released the first local rainstorm red warning signal this year. The release of this rainstorm red warning triggered the whole network release mechanism of the county red warning. At 15: 44, all mobile phone users in the county received the red warning message of rainstorm.

　　At the same time, the meteorological and hydrological departments, after joint consultation, judged that the Changjiang River would have a flood exceeding the warning level of 4 meters, which immediately blew the whistle of the county’s large-scale emergency transfer of people in low-lying areas.

　　In the Old Town Village of Fuliang Town, Yu Shunfa, a meteorological information officer, immediately reported to the two committees of the village after receiving the rainstorm red warning signal. The two committees of the village organized village cadres, backbone militia and party member to help the masses transfer. As of 20: 00 that night, there were 320 households with 1,351 people transferred from Old Town Village.

　　"Thank you so much!" On July 8, Dengsheng Wang, a villager who moved to safety before the flood, took Yu Shunfa’s hand and thanked him again and again.

　　At 3 am on the 8th, the flood peak water level of Changjiang River reached 33.14 meters, exceeding the warning water level by 4.64 meters, and the tributaries such as Jianxi River and Xiaobeigang experienced super-historical floods. When the flood peak reached Fuliang Town, the low-lying area was covered with Wang Yang. After dawn, Dengsheng Wang rushed to the hillside near his home and saw that the second floor of his home had been soaked in the flood.

　　During the rainstorm, Fuliang Town and nearly 20 townships including Jiangcun Township, Wanggang Township, Jinggongqiao Town and Legong Township urgently organized personnel transfer. As of 0: 00 on the 8th, 495 houses collapsed and damaged in Fuliang County due to the disaster, and 23,136 people were transferred urgently. Due to timely warning and effective prevention, there were no casualties.

　　(Source: China Meteorological News, July 13, 2020 Second Edition Editor: Zhang Lin)

　　　 Hail warning signals are divided into three levels, which are represented by yellow, orange and red respectively.

　　(A) the hail yellow warning signal

　　Icon:　

　　Standard: scattered hail may or has appeared in some areas within 6 hours, which may cause certain losses.

　　Forecast terms: forecast … … (Time), … … There will be scattered hail, which may cause some losses.

　　Defense guide:

　　1 local people’s governments at all levels, relevant departments and units shall do a good job in hail prevention and response according to their duties; The meteorological department started the preparation of artificial hail suppression operation and chose the opportunity to carry out the operation;

　　2. Strengthen crop protection measures and properly protect outdoor items or equipment such as cars that are vulnerable to hail attacks;

　　3. People should not go out at will, and outdoor pedestrians should take refuge in safe places, and don’t stay outdoors or in open places; Driving in the field should stop at an avoidable place as soon as possible;

　　4. Pay attention to the lightning disaster accompanied by hail weather.

　　(2) Hail orange warning signal

　　Icon:　

　　Standard: Hail weather may occur within 6 hours and may cause hail disaster.

　　Forecast terms: forecast … … (Time), … … There will be hail weather, which may cause hail disaster.

　　Defense guide:

　　1 local people’s governments at all levels, relevant departments and units shall, in accordance with their duties, do a good job in the emergency work of hail prevention; The meteorological department should prepare for the artificial hail suppression operation and choose the opportunity to carry out the operation;

　　2. Outdoor workers should temporarily stop work and take shelter indoors; Primary schools and kindergartens suspend outdoor activities to ensure the safety of students and children going to and from school;

　　3. Properly protect outdoor items or equipment that are vulnerable to hail attacks, and park cars in safe places such as garages;

　　4. Avoid going out and ensure that the elderly and children stay at home; Outdoor pedestrians take refuge in a safe place;

　　5. Lightning often happens with hail at the same time. Outdoor personnel should not enter isolated buildings, or stay in tall buildings, chimneys, telephone poles and big trees, but should take refuge in strong and lightning-proof places.

　　(3) Hail red warning signal

　　Icon:　

　　Standard: there is a great possibility of hail within 2 hours, and it may cause heavy hail disaster.

　　Forecast terms: forecast … … (Time), … … There will be hail weather, which may cause heavy hail disaster.

　　Defense guide:

　　1. The local people’s governments at all levels, relevant departments and units shall, in accordance with their duties, do a good job in the emergency and rescue of hail prevention, and the meteorological department shall carry out artificial hail prevention operations in a timely manner;

　　2. Stop all outdoor activities and guide people to a safe place; Primary and secondary schools and kindergartens take protective measures to ensure the safety of students and children in and out of school;

　　3. In case of hail during driving, stop at a safe place and sit in the car and wait for the hail to stop;

　　4. Personnel should not go out to ensure that the elderly and children stay at home; Outdoor pedestrians immediately go to a safe place to escape;

　　5. Indoor doors and windows should be closed, and outdoor items susceptible to hail, lightning and strong winds should be protected and placed; The vehicle is parked in a safe place such as a garage; Timely drive poultry and livestock into places with roofs;

　　6. Lightning often occurs with hail at the same time. Outdoor personnel should not enter isolated buildings, or stay in tall buildings, chimneys, telephone poles and big trees, but should take refuge in strong and lightning-proof places.

　　China Network November 9 According to the news of Quanzhou Municipal Government Information Office, Quanzhou Municipal Government Information Office informed Fujian Donggang Petrochemical Industry Co., Ltd. of the chemical leakage incident and its disposal. The following is the full text of the notification:

　　The following is the report on the chemical leakage incident and disposal of the dock of Fujian Donggang Petrochemical Industry Co., Ltd.:

　　I. What happened

　　At about 16: 00 on November 3, 2018, the "Cilan 1" tanker docked at the dock of Donggang Petrochemical Company in Quangang District, Quanzhou City; At 19: 20 on November 3, the loading operation of industrial cracked carbon nine began from the oil pipeline of Donggang Petrochemical Terminal; At 0: 51 am on November 4, the oil pipeline jumped; At 1: 13 a.m., the operators of Donggang Petrochemical Terminal found that the industrial cracking C9 chemical leaked during the loading process. On-site staff immediately took measures to stop the pump and close the valve, and entrusted qualified units to the dock to recover dirty oil quickly. At 1: 23 am, the oil stopped leaking; At 2 o’clock in the morning, the disposal unit rushed to the dock to recover the dirty oil; At 4: 30 in the morning, the cleaning operation in the oil boom basically ended. However, some dirty oil moved to the adjacent Xiaocuo sea area, and the air in some areas of Quangang appeared pungent smell. It was initially identified as an environmental pollution incident caused by a production safety accident.

　　Second, the disposal situation

　　After the incident, the main leaders of Quanzhou gave instructions at the first time, and rushed to the scene to guide the emergency response work, assigned the first-line dispatching command of the leaders in charge of the city, and asked Quangang District to immediately set up working groups such as on-site response, mass work, marine impact assessment and response, and incident investigation, and quickly carry out emergency response work separately: (1) Put the health and safety of the people first, do the oil pollution clean-up and environmental recovery work as quickly as possible, and invite professionals to participate in guiding the response work; (2) Do a good job in the dynamic monitoring of the atmosphere, water quality and aquatic products, as well as the medical observation of the impact on people’s health, timely and truly release information, and do a good job in the explanation of the people; (3) Start the damage assessment of farmers, coordinate and solve the problem of loss compensation according to law, and earnestly safeguard the legitimate rights and interests of the people; (4) Start to find out the cause of the incident and seriously investigate the responsibility of the relevant responsible persons; (5) Further improve the long-term mechanisms such as preventive inspection and emergency response, and organize large-scale investigation of petrochemical enterprises, so as to draw inferences from others and resolutely put an end to such incidents from happening again. At present, the work of incident handling is active and orderly.

　　By 15: 00 on the 8th, more than 400 ships, more than 2,500 people, 732 bags of oil-absorbing felt and 70 barrels of oil-cleaning agent had been dispatched to adsorb oil pollution, and the oil pollution floating in the affected sea areas had been basically cleaned up. Ships and personnel continue to be dispatched to adsorb the residual oil pollution on the shore, fishing rafts and so on, and this work is still going on.

　　As of 17: 00 on the 8th, Quangang District Hospital successively received 52 people suspected to be exposed to carbon nine leakage from the coastal areas of Nanpu Town and Houlong Town. The chief complaint of such patients is "physical discomfort after contact with irritating gas", and its main symptoms are dizziness, nausea, vomiting and pharyngeal discomfort. Among them, 42 cases were treated in outpatient department and 10 cases were observed in hospital. At present, the symptoms of 9 patients have improved significantly compared with those before admission; Another patient drowned in the incident waters and developed aspiration pneumonia. He has been transferred from ICU (intensive care unit) to general ward, and his condition is stable.

　　Iii. Environmental monitoring

　　Provincial and municipal environmental protection, marine fisheries, safety supervision and other departments started monitoring the atmosphere, marine environment and aquatic products in the affected areas from the 4th day. In terms of atmosphere, at 12: 00 on November 4th, the monitoring results of VOCs were 14.9mg/m3 in Shangxi Village (the village closest to the leakage point), 0.4934mg/m3 in Fengqian Village and 0.9756mg/m3 in Xiaocuo Village respectively. On November 4th, the monitoring results of VOCs in Shangxi Village decreased to 4.929mg/m3 at 3pm, and 0.429mg/m3 at 4pm. At 10: 00 am on November 5th, the monitoring results of VOCs were 0.0574mg/m3 in Shangxi Village, 0.5200mg/m3 in Fengqian Village and 0.7740mg/m3 in Xiaocuo Village. It remained between 0.018 mg/m3 and 0.239 mg/m3 from 6th to 7th, and between 0.102mg/m3 and 0.422mg/m3 at 11: 00 on 8th. Through synchronous analysis of VOCs, the concentrations of naphthalene and styrene in the air at 12: 00 on November 4 were 12.07mg/m3 and 1.77 mg/m3, respectively, accounting for 81% and 11.88% of VOCs in the air, and their concentrations were lower than the time-weighted average allowable concentration limit in the national occupational health standard "Hazardous Factors in the Workplace: Chemical Hazardous Factors in occupational exposure limits" (GBZ 2.1-2007).Among them, the time-weighted average allowable concentration limit of naphthalene is 50mg/m3, and the time-weighted average allowable concentration limit of styrene is 50mg/m3. Since then, the monitoring data of atmospheric environment are also less than the limit value of Occupational Exposure Limits of Hazardous Factors in Workplace (the above limit value refers to the allowable exposure level of repeated exposure for a long time in the process of occupational activities, which does not cause harmful effects to the health of most contacts). At present, Quanzhou Environmental Monitoring Center Station in Fujian Province is still continuously monitoring the atmospheric environmental quality. In terms of water quality, as detected by Quanzhou Marine Environment Monitoring and Forecasting Center, at about 10: 00 on the 6th, the oil content and chemical oxygen demand (COD) of the monitoring points in Xiaocuo cage culture area were 154.6ug/L and 0.86mg/L, respectively, and the oil content met the third seawater quality standard and the chemical oxygen demand met the first seawater quality standard. The content of petroleum and chemical oxygen demand at the monitoring point in the dock area of Donggang Petrochemical Company is 363.5ug/L and 0.79mg/L, respectively. The petroleum meets the fourth seawater quality standard and the chemical oxygen demand meets the first seawater quality standard. By the 7th, the chemical oxygen demand (COD) of the nine monitoring points had reached the first class seawater quality standard, and the oil had reached the first to third class water quality standards. On the 8th, the chemical oxygen demand (COD) of all 11 monitoring points reached the first class seawater quality standard, and the other 10 monitoring points met the first (second) class seawater quality standard for petroleum except Xiaocuo Wharf. In terms of aquatic products,The Provincial Marine and Fishery Monitoring Center took three samples from the aquaculture area at 9: 00 on the 4th for initial inspection. According to the inspection regulations, it is necessary to detect no cracked carbon nine residues for two weeks before the control can be lifted. In order to ensure food safety, Quangang District suspended the catching, selling and eating of cage-cultured aquatic products in the affected waters on the 4th. The incident directly affected the sea area of about 0.6 square kilometers, and the aquaculture damage was concentrated in Xiaocuo cage culture area of about 300 mu, involving 152 farmers and 99 units of culture area, of which 20 units were empty boxes, and 20 units of 79 units were seriously sunk, and the rest were damaged to varying degrees. On the 6th, we began to repair them, and on the 7th, we began to enter the farmers to investigate and evaluate the damage, so as to prepare for the next claim.

　　In the next step, the city will continue to do a good job in monitoring the atmosphere, marine environment, aquatic products, loss assessment and claims, incident investigation and responsibility determination; Pay close attention to the changes of related patients’ condition and do a good job in follow-up treatment; And continue to organize personnel to carry out home visits to ensure that the incident is handled in accordance with the law and regulations. Subsequent information will be released one after another.

    Xinhua News Agency, Beijing, May 1 (Xinhua) Recently, Tesla, an American electric vehicle manufacturer, issued a document in the official Weibo, saying that it would accelerate the landing of clean energy and autonomous driving technology, which triggered the market’s attention to Tesla’s "fully autonomous driving (FSD)" system. Then what is FSD? How is it different from the traditional assisted driving system?

    In recent years, many automobile manufacturers are developing automatic assisted driving systems, which make the on-board computers share more driving tasks, and Tesla is one of them. Tesla CEO elon musk once said: "Autopilot is a good thing on the plane, and we should also equip it on the car."

    FSD is the abbreviation of automated assisted driving system developed by Tesla, and its beta version was launched in 2020. The ultimate goal of the system is to realize that vehicles can identify road conditions, plan routes, control speed and direction independently without human intervention, and complete the driving from the starting point to the end point.

    However, some people have questioned the name "fully automatic driving", because according to the automatic driving classification standard of the National Highway Traffic Safety Administration of the United States, the vehicles currently running under this system are roughly in Level 2 (L2), that is, partially automated, but drivers still need to actively monitor road conditions and be ready to take over at any time. The truly fully automatic driving without the intervention of the driver is level 5 (L5), which can only be said to be the goal of future development.

    It is reported that the functions that can be realized by the current FSD system include automatic emergency braking (AEB), automatic lane change and traffic navigation, and also increase the ability of semi-autonomous navigation in urban streets and responding to traffic lights or stop signs.

    Many subsystems that make up FSD, such as automatic emergency braking, have matured and even become the common configuration of cars, and the National Highway Traffic Safety Administration of the United States requires it to become the standard for new cars. The composition of other manufacturers’ assisted driving systems is similar, but different from the traditional automobile manufacturer’s development system, Tesla’s FSD is based on neural network artificial intelligence algorithm, which imitates human driving through a lot of training and makes corresponding decisions and operations. Its automatic driving algorithm directly outputs control results according to the information sensed by sensors, imitates the operation of human drivers, and changes the "rule-driven" algorithm into a "data-driven" algorithm, thus simplifying model training.

    Tesla pushed the latest version of FSD V12.3.1 to North American car owners in March this year. Musk said in the previous test drive live broadcast that the FSD V12 version has been able to achieve an "end-to-end" artificial intelligence autopilot solution. Simply put, the scheme can directly output vehicle control instructions such as steering, acceleration and braking after inputting the image data obtained by the camera into the algorithm, which is more like a human brain, and can analyze and output control strategies only by relying on image data input. Previously, Tesla’s autonomous driving system relied on rule-based judgment, relying on car cameras to identify lanes, pedestrians, vehicles, signs and traffic lights, and then engineers wrote codes to deal with various situations.

    However, Tesla’s FSD system is still iterative and only available in the United States, Canada, Australia and some European countries. If FSD is to make continuous progress in the future, its security, data privacy, supervision and other challenges also need to be solved urgently.

Nicole Kidman will star in The Silent Wife.

　 　 1905 movie network news According to foreign media reports, Nicole Kidman will star in adrian lyne’s new film The Silent Wife, which is based on the best-selling novel of the same name.

　 　 It is reported that Nicole Kidman will play the protagonist Jody. Jody is faithful to her family. Although her husband has repeatedly made rash moves, she still contributes everything to this family. One day, she learned that her husband had abandoned her for a young woman, and the cheating object was actually her daughter’s best friend. Angry and ashamed, she didn’t want to admit her failure. By all means, the marriage on the verge slowly turned into a catch me if you can, and finally it came to a disastrous end.

The Cover of The Silent Wife

　 　 The film combines elements of crime, betrayal and lust, which is the specialty of director adrian lyne (masterpiece, and). Nicole Kidman, besides starring, will also be a film producer.